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题名: Insights from systems pharmacology into cardiovascular drug discovery and therapy
作者: Li, Peng1;  Fu, Yingxue1;  Ru, Jinlong1;  Huang, Chao1;  Du, Jiangfeng2;  Zheng, Chunli1;  Chen, Xuetong1;  Li, Pidong1;  Lu, Aiping3;  Yang, Ling4;  Wang, Yonghua1
关键词: Cardiovascular disease ;  Network pharmacology ;  Network analysis ;  Drug discovery ;  Drug-target network ;  Gene-disease network
刊名: BMC SYSTEMS BIOLOGY
发表日期: 2014-12-24
DOI: 10.1186/s12918-014-0141-z
卷: 8
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Mathematical & Computational Biology
研究领域[WOS]: Mathematical & Computational Biology
英文摘要: Background: Given the complex nature of cardiovascular disease (CVD), information derived from a systems-level will allow us to fully interrogate features of CVD to better understand disease pathogenesis and to identify new drug targets.
关键词[WOS]: HUMAN-DISEASE ;  NETWORK PHARMACOLOGY ;  HEART DEVELOPMENT ;  GENE ONTOLOGY ;  DISORDERS ;  PARADIGM ;  MUTATION ;  BIOLOGY ;  POLYPHARMACOLOGY ;  IDENTIFICATION
语种: 英语
WOS记录号: WOS:000350597000001
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/145780
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Northwest A&F Univ, Coll Life Sci, Ctr Bioinformat, Yang Iing 712100, Shaanxi, Peoples R China
2.Maastricht Univ, Dept Biochem, Cardiovasc Res Inst Maastricht, NL-6200 MD Maastricht, Netherlands
3.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Liaoning, Peoples R China

Recommended Citation:
Li, Peng,Fu, Yingxue,Ru, Jinlong,et al. Insights from systems pharmacology into cardiovascular drug discovery and therapy[J]. BMC SYSTEMS BIOLOGY,2014,8.
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