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Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of beta-agonists in swine hair
Chen, Xu1,2,3; Luo, Yong2,3; Shi, Bo1; Liu, Xianming4; Gao, Zhigang2,3; Du, Yuguang5; Zhao, Weijie2,3; Lin, Bingcheng2,3,4
Source PublicationANALYTICAL METHODS
2014
DOI10.1039/c4ay02116a
Volume6Issue:24Pages:9684-9690
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Life Sciences & Biomedicine ; Technology
WOS SubjectChemistry, Analytical ; Food Science & Technology ; Spectroscopy
WOS Research AreaChemistry ; Food Science & Technology ; Spectroscopy
WOS KeywordMASS-SPECTROMETRY ; CLENBUTEROL ; WITHDRAWAL ; CATTLE ; TIME ; HPLC
Abstractbeta-Agonists are a group of illegal but widely used feed additives in the stockbreeding industry. In order to achieve simple-to-use, fast and high-throughput testing of this banned chemical, herein we suggest a paper-based analytical device on which a chemiluminescence diminishment method was performed. In this approach, extracts from swine hair samples as well as luminescent reagents, such as luminol and potassium periodate solution, in a low volume were applied to our device. It was found that the light emission was diminished by the beta-agonists extracted from the swine hair samples. The degree of diminishment is proportional to the concentration of the beta-agonists from 1.0 x 10(-5) to 1.0 x 10(-8) mol L-1. Also, the concentrations of solutions for chemiluminescence were optimized. The mechanism and reaction kinetics of chemiluminescence were discussed as well. The detection limit was obtained as 1.0 x 10(-9) mol L-1, and recoveries from 96% to 110% were achieved, both of which suggested that our method will be favourable in field applications for swine hair samples.
Language英语
WOS IDWOS:000345451700022
Citation statistics
Cited Times:6[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/145813
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Agr Sci, Feed Res Inst, Beijing 100081, Peoples R China
2.Dalian Univ Technol, Sch Pharmaceut Sci & Technol, Dalian 116024, Peoples R China
3.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
5.Chinese Acad Sci, Inst Proc Engn, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Chen, Xu,Luo, Yong,Shi, Bo,et al. Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of beta-agonists in swine hair[J]. ANALYTICAL METHODS,2014,6(24):9684-9690.
APA Chen, Xu.,Luo, Yong.,Shi, Bo.,Liu, Xianming.,Gao, Zhigang.,...&Lin, Bingcheng.(2014).Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of beta-agonists in swine hair.ANALYTICAL METHODS,6(24),9684-9690.
MLA Chen, Xu,et al."Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of beta-agonists in swine hair".ANALYTICAL METHODS 6.24(2014):9684-9690.
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