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In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences
Sun, Dongxue1; Zhu, Liangliang2; Xiao, Ling3; Xia, Yangliu4; Ge, Guangbo4; Cao, Yunfeng4; Wu, Yan2; Yin, Jun1; Yang, Ling4
关键词Armillarisin a Liver Microsomal Glucuronidation Species Difference Udp-glucuronosyltranferases
刊名XENOBIOTICA
2014-11-01
DOI10.3109/00498254.2014.927084
44期:11页:988-995
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Pharmacology & Pharmacy ; Toxicology
研究领域[WOS]Pharmacology & Pharmacy ; Toxicology
关键词[WOS]TANDEM MASS-SPECTROMETRY ; MESSENGER-RNA EXPRESSION ; HUMAN LIVER ; INTESTINAL GLUCURONIDATION ; DRUG GLUCURONIDATION ; CYTOCHROME-P450 ; INHIBITION ; METABOLISM ; ISOFORMS ; IDENTIFICATION
英文摘要1. This study is performed to investigate liver microsomal glucuronidation of Armillarisin A (A.A), an effective cholagogue drug, aiming at characterizing the involved UDP-glucuronosyltranferases (UGT) and revealing potential species differences.
语种英语
WOS记录号WOS:000343080900004
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/145893
专题中国科学院大连化学物理研究所
作者单位1.Shenyang Pharmaceut Univ, Sch Tradit Chinese Med, Dept Tradit Chinese Med Resources, Shenyang, Peoples R China
2.Anqing Normal Univ, Sch Life Sci, Lab Drug & Food Safety Evaluat, Anqing, Peoples R China
3.Anqing Normal Univ, Lab Resources & Environm, Anqing, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China
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GB/T 7714
Sun, Dongxue,Zhu, Liangliang,Xiao, Ling,et al. In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences[J]. XENOBIOTICA,2014,44(11):988-995.
APA Sun, Dongxue.,Zhu, Liangliang.,Xiao, Ling.,Xia, Yangliu.,Ge, Guangbo.,...&Yang, Ling.(2014).In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences.XENOBIOTICA,44(11),988-995.
MLA Sun, Dongxue,et al."In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences".XENOBIOTICA 44.11(2014):988-995.
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