中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate
作者: Liu, Lei1, 2;  Yang, Dapeng1, 3;  Li, Peng1
刊名: JOURNAL OF PHYSICAL CHEMISTRY B
发表日期: 2014-10-09
DOI: 10.1021/jp5082017
卷: 118, 期:40, 页:11707-11714
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Physical
研究领域[WOS]: Chemistry
英文摘要: The pH-related fluorescence quenching mechanism of 2-amino-4-hydroxypteridine (pterin), a biologic functional molecule, in the presence of acetate ion has been fully investigated for the first time. Using a combined experimental and theoretical approach, we discover that the fluorescence quenching observed in acid condition originated from a barrierless excited-state proton-transfer process. The proton on the acid form of pterin is transferred to acetate after photoexcitation. The hydrogen-bonding patterns are found to change with the pH values that govern the occurrence of excited-state proton transfer (ESPT). As revealed by investigating the excitation and relaxation processes of pterin, this ESPT process shows impressive site specificity intrinsically due to the photoinduced acidic center shifting. The experimentally observed fluorescence quenching and lifetime shortening of pterin in acid condition are thus attributed to the site-specific proton transfer from the N5 site. Pterin exists extensively in living organisms and has been found to show favorable proton-donating ability, which may transfer its proton to biofunctional molecules with hydrogen-accepting groups and induce related bioeffects.
关键词[WOS]: 2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE ;  ELECTRON-TRANSFER ;  AQUEOUS-SOLUTION ;  FOLIC-ACID ;  FLUORESCENCE ;  MECHANISM ;  TETRAHYDROBIOPTERIN ;  BIOSYNTHESIS ;  METABOLISM ;  PTERIDINES
语种: 英语
WOS记录号: WOS:000343016000012
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/145922
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
2.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
3.North China Univ Water Resources & Elect Power, Phys Lab, Zhengzhou 450045, Peoples R China

Recommended Citation:
Liu, Lei,Yang, Dapeng,Li, Peng. pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2014,118(40):11707-11714.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Liu, Lei]'s Articles
 [Yang, Dapeng]'s Articles
 [Li, Peng]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Liu, Lei]‘s Articles
 [Yang, Dapeng]‘s Articles
 [Li, Peng]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace