DICP OpenIR
Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice
Huang, Huimei1,2; Yang, Yongge3; Lv, Chao2; Chang, Wanlin2; Peng, Chengcheng4; Wang, Shuping1; Ge, Guangbo5; Han, Lin1; Zhang, Weidong1,2,3; Liu, Runhui1,2
关键词Bufadienolides Shexiang Baoxin Pill Pharmacokinetic Tissue Distribution Lc-esi-ms/ms
刊名JOURNAL OF ETHNOPHARMACOLOGY
2015-02-23
DOI10.1016/jjep.2014.07.056
161页:175-185
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
关键词[WOS]TANDEM MASS-SPECTROMETRY ; RAT PLASMA ; TOAD VENOM ; CHROMATOGRAPHY ; EXTRACT ; HPLC ; CONSTITUENTS ; IONIZATION ; INDUCTION ; CHANSU
英文摘要Ethnopharmacological relevance: Shexiang Baoxin Pill (SBP) is a well-known composite formula of traditional Chinese medicine (TCM), widely used to treat cardiovascular diseases such as angina pectoris and myocardial infarction. Bufadienolides are major active compounds of Venenum Bufonis, which is one of the seven materiamedicas that comprise the Shexiang Baoxin Pill. Previous pharmacokinetics studies of bufadienolides have typically used a single medicinal material delivered to rats. In this study, we have chosen the mouse, a more proper animal model than the rat, to investigate the in vivo pharmacokinetics and tissue distribution of bufadienolides from the Shexiang Baoxin Pill.
语种英语
WOS记录号WOS:000349731100022
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/145985
专题中国科学院大连化学物理研究所
作者单位1.Second Mil Med Univ, Sch Pharm, Shanghai 200433, Peoples R China
2.Fujian Univ Tradit Chinese Med, Sch Pharm, Fuzhou 350108, Fujian, Peoples R China
3.Beijing Mil Command Gen Hosp, Dept Clin Pharmacol, Beijing 100700, Peoples R China
4.Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
5.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Huang, Huimei,Yang, Yongge,Lv, Chao,et al. Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice[J]. JOURNAL OF ETHNOPHARMACOLOGY,2015,161:175-185.
APA Huang, Huimei.,Yang, Yongge.,Lv, Chao.,Chang, Wanlin.,Peng, Chengcheng.,...&Liu, Runhui.(2015).Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice.JOURNAL OF ETHNOPHARMACOLOGY,161,175-185.
MLA Huang, Huimei,et al."Pharmacokinetics and tissue distribution of five bufadienolides from the Shexiang Baoxin pill following oral administration to mice".JOURNAL OF ETHNOPHARMACOLOGY 161(2015):175-185.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Huang, Huimei]的文章
[Yang, Yongge]的文章
[Lv, Chao]的文章
百度学术
百度学术中相似的文章
[Huang, Huimei]的文章
[Yang, Yongge]的文章
[Lv, Chao]的文章
必应学术
必应学术中相似的文章
[Huang, Huimei]的文章
[Yang, Yongge]的文章
[Lv, Chao]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。