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题名: Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging
作者: Liu, Meiying1;  Zhang, Xiqi2, 3;  Yang, Bin2, 3;  Li, Zhan4;  Deng, Fengjie1;  Yang, Yang1;  Zhang, Xiaoyong1, 2, 3;  Wei, Yen2, 3
关键词: Starch ;  Polyethyleneimine ;  Fluorescent organic nanoparticles ;  Cell imaging ;  Biomedical applications
刊名: CARBOHYDRATE POLYMERS
发表日期: 2015-05-05
DOI: 10.1016/j.carbpol.2014.12.047
卷: 121, 页:49-55
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Applied ;  Chemistry, Organic ;  Polymer Science
研究领域[WOS]: Chemistry ;  Polymer Science
英文摘要: Fluorescent organic nanoparticles (FONs) based on carbohydrate polymers were prepared through one-pot hydrothermal treatment of starch in the presence of polyethyleneimine. These FONs (named as PEI-Starch FONs) were characterized by a series of techniques including UV Vis absorption spectroscopy, fluorescent spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscopy and X-ray photoelectron spectroscopy. Results showed that the size of PEI-Starch FONs is 10-30 nm. The PEI-Starch FONs exhibited high water dispersibility because of the existence of hydrophilic functional groups on their surface. After excited with different wavelength, PEI-Starch FONs emitted strong and excitation-dependent fluorescence. To evaluate their potential for biomedical applications, biocompatibility and cell uptake behavior of PEI-Starch FONs were further investigated. We demonstrated that PEI-Starch FONs are biocompatible with cells and can be easily internalized by cells within 3 h. Taken together, novel FONs have been prepared via a simple and scalable hydrothermal method using starch and polyethyleneimine as precursors. These PEI-Starch FONs showed excellent fluorescence properties, high water dispersibility and good biocompatibility, making them highly potential for various biomedical applications. (C) 2015 Elsevier Ltd. All rights reserved.
关键词[WOS]: AGGREGATION-INDUCED EMISSION ;  CELL IMAGING APPLICATIONS ;  ORGANIC NANOPARTICLES ;  QUANTUM DOTS ;  CARBON-DOTS ;  BIOCOMPATIBILITY EVALUATION ;  ANILINE OLIGOMERS ;  DRUG-DELIVERY ;  FABRICATION ;  DYE
语种: 英语
WOS记录号: WOS:000350182400006
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146045
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Nanchang Univ, Inst Polymers, Dept Chem, Nanchang 330031, Peoples R China
2.Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China
3.Tsinghua Univ, Tsinghua Ctr Frontier Polymer Res, Beijing 100084, Peoples R China
4.Chinese Acad Sci, Inst Chem Phys, Key Lab Nat Med Gansu Prov, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Gansu, Peoples R China

Recommended Citation:
Liu, Meiying,Zhang, Xiqi,Yang, Bin,et al. Fluorescent nanoparticles from starch: Facile preparation, tunable luminescence and bioimaging[J]. CARBOHYDRATE POLYMERS,2015,121:49-55.
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