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题名: Regulation profile of phosphatidylcholines (PCs) and lysophosphatidylcholines (LPCs) components towards UDP-glucuronosyltransferases (UGTs) isoforms
作者: Gao, Xin1;  Qu, Hengyan1;  Ai, Chun-Zhi3, 4;  Cao, Yun-Feng5;  Huang, Ting5;  Chen, Jian-Xing5;  Zeng, Jia5;  Sun, Xiao-Yu3, 4;  Hong, Mo3, 4;  Gonzalez, Frank J.6;  Liu, Zeyuan1;  Fang, Zhong-Ze2
关键词: Allosteric activation ;  lysophosphatidylcholines ;  phosphatidylcholine ;  UDP-glucuronosyltransferases
刊名: XENOBIOTICA
发表日期: 2015-03-01
DOI: 10.3109/00498254.2014.966174
卷: 45, 期:3, 页:197-206
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Pharmacology & Pharmacy ;  Toxicology
研究领域[WOS]: Pharmacology & Pharmacy ;  Toxicology
英文摘要: 1. Endogenous compounds have been reported to be the regulators of UDP-glucuronosyltransferases (UGTs) isoforms. This study aims to investigate the regulatory effects of the activity of UGT isoforms by two important lipid components phosphatidylcholine (PC) and lysophosphatidylcholines (LPC) using in vitro incubation system.
关键词[WOS]: ACID ;  IDENTIFICATION ;  PHOSPHOLIPIDS ;  INHIBITION
语种: 英语
WOS记录号: WOS:000350451700002
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146047
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Acad Mil Med Sci, Affiliated Hosp, Dept Clin Pharmacol, Beijing, Peoples R China
2.Tianjin Med Univ, Sch Publ Hlth, Dept Toxicol, Tianjin, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Joint Ctr Translat Med, Dalian, Peoples R China
4.Liaoning Med Univ, Affiliated Hosp 1, Dalian, Peoples R China
5.Shanghai Inst Planned Parenthood Res, Shanghai Engn & Technol Res Ctr Reprod Hlth Drug, Key Lab Contracept & Devices Res NPFPC, Shanghai, Peoples R China
6.NCI, Lab Metab, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

Recommended Citation:
Gao, Xin,Qu, Hengyan,Ai, Chun-Zhi,et al. Regulation profile of phosphatidylcholines (PCs) and lysophosphatidylcholines (LPCs) components towards UDP-glucuronosyltransferases (UGTs) isoforms[J]. XENOBIOTICA,2015,45(3):197-206.
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