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题名: Four-component reaction leading to highly functionalized sulfoalkoxy carbonyl compounds
作者: Sohail, Muhammad1;  Zhang, Yixin1;  Sun, Guangwei1;  Guo, Xin1;  Liu, Wujun1;  Liu, Chang1;  Zhao, Zongbao K.1
刊名: CHEMICAL COMMUNICATIONS
发表日期: 2015
DOI: 10.1039/c4cc10403j
卷: 51, 期:23, 页:4774-4777
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: A facile regio- and diastereoselective four-component protocol has been developed involving an alpha,beta-unsaturated carbonyl compound, a cyclic ether, a sulfonic acid and a halogen reagent to access highly anti-alpha-bromo-beta-sulfoalkoxyl carbonyl derivatives. Some of these products have high toxicity against human chronic myeloid leukemia cells.
关键词[WOS]: ASYMMETRIC CONJUGATE ADDITION ;  INTERSTRAND CROSS-LINKING ;  ENANTIOSELECTIVE SYNTHESIS ;  MULTICOMPONENT REACTIONS ;  IN-VITRO ;  DIMETHANESULFONATE ESTERS ;  CARBENE COMPLEXES ;  ORGANIC-SYNTHESIS ;  BRONSTED ACIDS ;  ALLENIC ESTERS
语种: 英语
WOS记录号: WOS:000351056200005
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146058
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China

Recommended Citation:
Sohail, Muhammad,Zhang, Yixin,Sun, Guangwei,et al. Four-component reaction leading to highly functionalized sulfoalkoxy carbonyl compounds[J]. CHEMICAL COMMUNICATIONS,2015,51(23):4774-4777.
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