中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Substitution of alcohols by N-nucleophiles via transition metal-catalyzed dehydrogenation
作者: Yang, Qin1;  Wang, Qingfu1;  Yu, Zhengkun1, 2
刊名: CHEMICAL SOCIETY REVIEWS
发表日期: 2015
DOI: 10.1039/c4cs00496e
卷: 44, 期:8, 页:2305-2329
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: Transition metal-catalyzed substitution of alcohols by N-nucleophiles (or N-alkylation of amines and related compounds with alcohols) avoids the use of alkylating agents by means of borrowing hydrogen (BH) activation of the alcohol substrates. Water is produced as the only by-product, which makes the "BH'' processes atom-economic and environmentally benign. Diverse types of homogeneous organometallic and heterogeneous transition metal catalysts, and substrates such as N-nucleophiles including amines, amides, sulfonamides and ammonia, and various alcohols, can be used for this purpose, demonstrating the promising potential of "BH'' processes to replace the procedures using traditional alkylating agents in pharmaceutical and chemical industries. Borrowing hydrogen activation of alcohols for C-N bond formation has recently been paid more and more attention, and a lot of new and novel procedures and examples have been documented. This critical review summarizes the recent advances in "BH'' substitution of alcohols by N-nucleophiles since 2009. "Semi-BH'' N-alkylation processes with or without an external hydrogen acceptor are also briefly presented. Suitable discussion of the "BH'' strategy provides new principles for establishing green processes to replace the relevant traditional synthetic methods for C-N bond formation.
关键词[WOS]: BORROWING HYDROGEN METHODOLOGY ;  SUPPORTED RUTHENIUM HYDROXIDE ;  MILD REACTION CONDITIONS ;  ONE-POT SYNTHESIS ;  PRIMARY AMINES ;  SELECTIVE ALKYLATION ;  SECONDARY ALCOHOLS ;  DIRECT AMINATION ;  IRIDIUM COMPLEX ;  TERTIARY-AMINES
语种: 英语
WOS记录号: WOS:000352899500011
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146196
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

Recommended Citation:
Yang, Qin,Wang, Qingfu,Yu, Zhengkun. Substitution of alcohols by N-nucleophiles via transition metal-catalyzed dehydrogenation[J]. CHEMICAL SOCIETY REVIEWS,2015,44(8):2305-2329.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Yang, Qin]'s Articles
 [Wang, Qingfu]'s Articles
 [Yu, Zhengkun]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Yang, Qin]‘s Articles
 [Wang, Qingfu]‘s Articles
 [Yu, Zhengkun]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace