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Proteomic profiling of protein corona formed on the surface of nanomaterial
Zhang, Hongyan1,2; Wu, Ren'an1
关键词Protein Corona Nanomaterial Proteomics Mass Spectrometry Identification And Quantification Gel Electrophoresis
刊名SCIENCE CHINA-CHEMISTRY
2015-05-01
DOI10.1007/s11426-015-5395-9
58期:5页:780-792
收录类别SCI
文章类型Review
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]QUANTITATIVE PROTEOMICS ; MASS-SPECTROMETRY ; NANOPARTICLE SIZE ; PLASMA-PROTEINS ; DRUG-DELIVERY ; MAGNETIC NANOPARTICLES ; SILICA NANOPARTICLES ; ADSORPTION PATTERNS ; SAMPLE PREPARATION ; DIGESTION
英文摘要The formation of protein coronas on nanomaterial will significantly alter the surface properties of nanomaterial in biological systems and subsequently impact biological responses including signaling, cellular uptake, transport, and toxicity etc. It is of critical importance to understand the formation of protein coronas on the surface of nanomaterial. Analytical techniques, especially mass spectrometry-based proteomics methods, are playing a key role for the qualitative and quantitative analyses of protein coronas on nanomaterial. In this review, the proteomic approaches developed for the characterization of protein coronas on various nanomaterials are introduced with the emphasis on the mass spectrometry-based proteomic strategies.
语种英语
WOS记录号WOS:000354188900005
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文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/146226
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Zhang, Hongyan,Wu, Ren'an. Proteomic profiling of protein corona formed on the surface of nanomaterial[J]. SCIENCE CHINA-CHEMISTRY,2015,58(5):780-792.
APA Zhang, Hongyan,&Wu, Ren'an.(2015).Proteomic profiling of protein corona formed on the surface of nanomaterial.SCIENCE CHINA-CHEMISTRY,58(5),780-792.
MLA Zhang, Hongyan,et al."Proteomic profiling of protein corona formed on the surface of nanomaterial".SCIENCE CHINA-CHEMISTRY 58.5(2015):780-792.
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