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题名: Redox-Responsive Fluorescent Probes with Different Design Strategies
作者: Lou, Zhangrong1;  Li, Peng1;  Han, Keli1
刊名: ACCOUNTS OF CHEMICAL RESEARCH
发表日期: 2015-05-01
DOI: 10.1021/acs.accounts.5b00009
卷: 48, 期:5, 页:1358-1368
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要: In an aerobic organism, reactive oxygen species (ROS) are an inevitable metabolic byproduct. Endogenously produced ROS have a significant role in physiological processes, but excess ROS can cause oxidative stress and can damage tissue. Cells possess elaborate mechanisms to regulate their internal redox status. The intracellular redox homeostasis plays an essential role in maintaining Cellular function. However, moderate alterations in redox balance can accompany major transitions in a cell's life cycle. Because of the role of ROS in physiology and in pathology, researchers need new tools to study redox chemistry in biological systems.
关键词[WOS]: THIOLS REDUCING REPAIR ;  H2O2 OXIDATIVE STRESS ;  STATE PROTON-TRANSFER ;  LIVING CELLS ;  GLUTATHIONE-PEROXIDASE ;  REACTIVE OXYGEN ;  TD-DFT ;  SENSING MECHANISM ;  FREE-RADICALS ;  ENDOPLASMIC-RETICULUM
语种: 英语
WOS记录号: WOS:000355055700016
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146269
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China

Recommended Citation:
Lou, Zhangrong,Li, Peng,Han, Keli. Redox-Responsive Fluorescent Probes with Different Design Strategies[J]. ACCOUNTS OF CHEMICAL RESEARCH,2015,48(5):1358-1368.
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