DICP OpenIR
Ultrasmall single micelle@resin core-shell nanocarriers as efficient cargo loading vehicles for in vivo biomedical applications
Yang, Yan1; Song, Xiaojie2; Yao, Yi1; Wu, Hao2; Liu, Jian1; Zhao, Yaopeng1; Tan, Mingqian2; Yang, Qihua1
Source PublicationJOURNAL OF MATERIALS CHEMISTRY B
2015
DOI10.1039/c5tb00398a
Volume3Issue:23Pages:4671-4678
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Technology
WOS SubjectMaterials Science, Biomaterials
WOS Research AreaMaterials Science
WOS KeywordQUANTUM DOTS ; HYDROTHERMAL SYNTHESIS ; FORMALDEHYDE POLYMER ; CARBON NANOSPHERES ; BLOCK-COPOLYMERS ; STOBER METHOD ; SILICA ; NANOPARTICLES ; SPHERES ; FABRICATION
AbstractUltrasmall core-shell nanocarriers (NCs) are believed to be ideal candidates for biological applications, as proved by silica-based core-shell NCs fabricated using a single micelle as a template. Compared with inert silica, polymers with various properties play an essential and ubiquitous role in our daily life. However, the fabrication of polymer-based NCs with ultrasmall particle size (less than 20 nm) is still very limited, which is probably hindered due to the difficulty in handling the polymeric process and the soft nature of most polymers. In this study, we demonstrated the fabrication of ultrasmall single micelle@resin core-shell NCs through a single micelle template method using resorcinol-formaldehyde resins (RFRs) as model polymers. Moreover, the fluorescence properties of the ultrasmall single micelle@resin core-shell NCs could be adjusted from visible light to near-infrared through the incorporation of different dye molecules. The fluorescent single micelle@RFR core-shell NCs show extra-low cytotoxicity and great potential in both in vitro and in vivo bioimaging and photothermal therapy applications.
Language英语
WOS IDWOS:000355737600006
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/146292
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Yang, Yan,Song, Xiaojie,Yao, Yi,et al. Ultrasmall single micelle@resin core-shell nanocarriers as efficient cargo loading vehicles for in vivo biomedical applications[J]. JOURNAL OF MATERIALS CHEMISTRY B,2015,3(23):4671-4678.
APA Yang, Yan.,Song, Xiaojie.,Yao, Yi.,Wu, Hao.,Liu, Jian.,...&Yang, Qihua.(2015).Ultrasmall single micelle@resin core-shell nanocarriers as efficient cargo loading vehicles for in vivo biomedical applications.JOURNAL OF MATERIALS CHEMISTRY B,3(23),4671-4678.
MLA Yang, Yan,et al."Ultrasmall single micelle@resin core-shell nanocarriers as efficient cargo loading vehicles for in vivo biomedical applications".JOURNAL OF MATERIALS CHEMISTRY B 3.23(2015):4671-4678.
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