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题名: DanHong injection dose-dependently varies amino acid metabolites and metabolic pathways in the treatment of rats with cerebral ischemia
作者: Guo, Zhi-li1, 2;  Zhu, Yan1, 3, 4;  Su, Xiao-tao4;  Liu, Jun1;  Yang, Qian-xu5;  Nan, Jing-yi4;  Zhao, Bu-chang4;  Zhang, Ying-ying1;  Yu, Ya-nan1;  Li, Bing1;  Xiao, Hong-bin5;  Wang, Zhong1
关键词: DanHong injection ;  traditional Chinese medicine ;  cerebral ischemia ;  amino acid metabolomics ;  metabolic pathways
刊名: ACTA PHARMACOLOGICA SINICA
发表日期: 2015-06-01
DOI: 10.1038/aps.2014.167
卷: 36, 期:6, 页:748-757
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences ;  Life Sciences & Biomedicine
类目[WOS]: Chemistry, Multidisciplinary ;  Pharmacology & Pharmacy
研究领域[WOS]: Chemistry ;  Pharmacology & Pharmacy
英文摘要: Aim: To determine how the relative amino acid contents and metabolic pathways regulate the pharmacological phenotypes in rats with cerebral ischemia after treatment with varying doses of DanHong injection (DHI).
关键词[WOS]: CHROMATOGRAPHY-MASS SPECTROMETRY ;  ARTERY OCCLUSION ;  REPERFUSION INJURY ;  METABONOMICS ;  MODEL ;  PLASMA
语种: 英语
WOS记录号: WOS:000355840600012
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146300
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing 100700, Peoples R China
2.Zhejiang Chinese Med Univ, Jiaxing Tradit Chinese Med Affiliated, Jiaxing 314000, Peoples R China
3.Capital Med Univ, Beijing Elect Power Hosp, Beijing 100073, Peoples R China
4.Xian Buchang Pharmaceut Co Ltd, Xian 712000, Peoples R China
5.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China

Recommended Citation:
Guo, Zhi-li,Zhu, Yan,Su, Xiao-tao,et al. DanHong injection dose-dependently varies amino acid metabolites and metabolic pathways in the treatment of rats with cerebral ischemia[J]. ACTA PHARMACOLOGICA SINICA,2015,36(6):748-757.
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