DICP OpenIR
Synthesis of a hydrophilic maltose functionalized Au NP/PDA/Fe3O4-RGO magnetic nanocomposite for the highly specific enrichment of glycopeptides
Bi, Changfen1,2; Jiang, Ruidong1,2; He, Xiwen1,2; Chen, Langxing1,2; Zhang, Yukui1,2,3
刊名RSC ADVANCES
2015
DOI10.1039/c5ra06911d
5期:73页:59408-59416
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]INTERACTION LIQUID-CHROMATOGRAPHY ; SELECTIVE ENRICHMENT ; AFFINITY-CHROMATOGRAPHY ; FACILE PREPARATION ; MASS-SPECTROMETRY ; CLICK MALTOSE ; NANOPARTICLES ; GRAPHENE ; GLYCOSYLATION ; PHASE
英文摘要The development of methods to isolate and enrich low-abundance glycopeptides is an important prerequisite for glycoproteomics research. In this study, a hydrophilic maltose functionalized Au nanoparticle (NP)/polydopamine (PDA)/Fe3O4-reduced graphene oxide (RGO) nanocomposite has been successfully synthesized in mild conditions. The bioadhesive polydopamine film was prepared by self-polymerization on the surface of Fe3O4-graphene oxide, which not only prevents the agglomeration of the graphene sheets and enhances the specific surface area, but also facilitates the Au NP immobilization. A great number of loading Au NPs possess the highly available surface area for the immobilization of the high density of the thiol-terminated maltose via Au-S bonds. The resulting Au NP-maltose/PDA/Fe3O4-RGO nanocomposite exhibits excellent environmental stability, good biocompatibility and water dispersibility. Furthermore, the highly loaded Fe3O4 NPs make the enrichment very convenient. With all of these advances, the novel Au NP-maltose/PDA/Fe3O4-RGO nanocomposite presents selective enrichment of the glycopeptides from a low concentration of horseradish peroxidase tryptic digest (0.1 ng mu L-1).
语种英语
WOS记录号WOS:000357961800056
引用统计
被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/146395
专题中国科学院大连化学物理研究所
作者单位1.Nankai Univ, Tianjin Key Lab Biosensing & Mol Recognit, Coll Chem, Res Ctr Analyt Sci,State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China
2.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Bi, Changfen,Jiang, Ruidong,He, Xiwen,et al. Synthesis of a hydrophilic maltose functionalized Au NP/PDA/Fe3O4-RGO magnetic nanocomposite for the highly specific enrichment of glycopeptides[J]. RSC ADVANCES,2015,5(73):59408-59416.
APA Bi, Changfen,Jiang, Ruidong,He, Xiwen,Chen, Langxing,&Zhang, Yukui.(2015).Synthesis of a hydrophilic maltose functionalized Au NP/PDA/Fe3O4-RGO magnetic nanocomposite for the highly specific enrichment of glycopeptides.RSC ADVANCES,5(73),59408-59416.
MLA Bi, Changfen,et al."Synthesis of a hydrophilic maltose functionalized Au NP/PDA/Fe3O4-RGO magnetic nanocomposite for the highly specific enrichment of glycopeptides".RSC ADVANCES 5.73(2015):59408-59416.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Bi, Changfen]的文章
[Jiang, Ruidong]的文章
[He, Xiwen]的文章
百度学术
百度学术中相似的文章
[Bi, Changfen]的文章
[Jiang, Ruidong]的文章
[He, Xiwen]的文章
必应学术
必应学术中相似的文章
[Bi, Changfen]的文章
[Jiang, Ruidong]的文章
[He, Xiwen]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。