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题名: Investigation of spherical hydrogel surface with optical interferometer
作者: Zheng, Huizhen1, 4;  Xie, Hongguo1;  Wu, Hao1, 4;  Wang, Feng3;  Liu, Xiudong2;  Yu, Weiting1;  Ma, Xiaojun1
关键词: Hydrogel microspheres ;  Surface morphology ;  Optical interferometer ;  In wet ;  In situ
刊名: COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
发表日期: 2015-11-05
DOI: 10.1016/j.colsurfa.2015.08.028
卷: 484, 页:457-462
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Physical
研究领域[WOS]: Chemistry
英文摘要: Surface morphology of calcium alginate hydrogel microspheres (CAHM) with ultrahigh water content has been found to affect the interaction with proteins and cells in vivo. In this study, an optical interferometer is developed to firstly characterize spherical surface morphology of CAHM in wet and in situ under normal pressure and temperature. CAHM shows smoother surface with significant lower roughness than flat alginate membrane, which also contribute to significantly different surface morphology between spherical microcapsules and flat membrane after coating with chitosan. These results help to update the previous knowledge that flat surface can be used to simulate spherical surface for understanding hydrogel behavior to protein adsorption. Meanwhile, CAHM is characterized by SEM techniques with drying process at varying degrees, which demonstrates deviated surface morphology to the original wet surface. Therefore, the optical interferometer is proved a useful tool to acquire the authentic and accurate surface information of spherical hydrogels at applied wet state. (C) 2015 Elsevier B.V. All rights reserved.
关键词[WOS]: ALGINATE ;  CHITOSAN ;  BEADS
语种: 英语
WOS记录号: WOS:000362130100053
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/146573
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Dalian Univ, Coll Environm & Chem Engn, Dalian Econ Technol Dev Zone, Dalian 116622, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Opt Fabricat & Coating, Dalian 116023, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China

Recommended Citation:
Zheng, Huizhen,Xie, Hongguo,Wu, Hao,et al. Investigation of spherical hydrogel surface with optical interferometer[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2015,484:457-462.
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