DICP OpenIR
Investigation of spherical hydrogel surface with optical interferometer
Zheng, Huizhen1,4; Xie, Hongguo1; Wu, Hao1,4; Wang, Feng3; Liu, Xiudong2; Yu, Weiting1; Ma, Xiaojun1
KeywordHydrogel Microspheres Surface Morphology Optical Interferometer In Wet In Situ
Source PublicationCOLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
2015-11-05
DOI10.1016/j.colsurfa.2015.08.028
Volume484Pages:457-462
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Physical
WOS Research AreaChemistry
WOS KeywordALGINATE ; CHITOSAN ; BEADS
AbstractSurface morphology of calcium alginate hydrogel microspheres (CAHM) with ultrahigh water content has been found to affect the interaction with proteins and cells in vivo. In this study, an optical interferometer is developed to firstly characterize spherical surface morphology of CAHM in wet and in situ under normal pressure and temperature. CAHM shows smoother surface with significant lower roughness than flat alginate membrane, which also contribute to significantly different surface morphology between spherical microcapsules and flat membrane after coating with chitosan. These results help to update the previous knowledge that flat surface can be used to simulate spherical surface for understanding hydrogel behavior to protein adsorption. Meanwhile, CAHM is characterized by SEM techniques with drying process at varying degrees, which demonstrates deviated surface morphology to the original wet surface. Therefore, the optical interferometer is proved a useful tool to acquire the authentic and accurate surface information of spherical hydrogels at applied wet state. (C) 2015 Elsevier B.V. All rights reserved.
Language英语
WOS IDWOS:000362130100053
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/146573
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Dalian Univ, Coll Environm & Chem Engn, Dalian Econ Technol Dev Zone, Dalian 116622, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Opt Fabricat & Coating, Dalian 116023, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Zheng, Huizhen,Xie, Hongguo,Wu, Hao,et al. Investigation of spherical hydrogel surface with optical interferometer[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2015,484:457-462.
APA Zheng, Huizhen.,Xie, Hongguo.,Wu, Hao.,Wang, Feng.,Liu, Xiudong.,...&Ma, Xiaojun.(2015).Investigation of spherical hydrogel surface with optical interferometer.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,484,457-462.
MLA Zheng, Huizhen,et al."Investigation of spherical hydrogel surface with optical interferometer".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 484(2015):457-462.
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