中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Synthesis of Water-Dispersible Mn2+ Functionalized Silicon Nanoparticles under Room Temperature and Atmospheric Pressure for Fluorescence and Magnetic Resonance Dual-Modality Imaging
作者: Dou, Ya-Kun1;  Chen, Yang2;  He, Xi-Wen1;  Li, Wen-You1, 3;  Li, Yu-Hao2;  Zhang, Yu-Kui1, 4
刊名: ANALYTICAL CHEMISTRY
发表日期: 2017-11-07
DOI: 10.1021/acs.analchem.7b01644
卷: 89, 期:21, 页:11286-11292
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: Silicon nanoparticles (Si NPs) have been widely used in fluorescence imaging. However, rigorous synthesis conditions and the single modality imaging limit the further development of Si NPs in the field of biomedical imaging. Here, we reported a method for synthesizing water-dispersible Mn2+ functionalized Si NPs (Mn-Si NPs) under mild experimental conditions for fluorescence and magnetic resonance dual-modality imaging. The whole synthesis process was completed under room temperature and atmospheric pressure, and no special and expensive equipment was required. The synthetic nanoparticles, with favorable pH stability, NaCl stability, photostability, and low toxicity, emitted green fluorescence (512 nrn). At the same time, the nanoparticles also demonstrated excellent magnetic resonance imaging ability. In vitro, their T-1-weighted magnetic resonance imaging effect was obvious, and the value of longitudinal relaxation degree r(1) reached 4.25 mM(-1) s(-1). On the basis of their good biocompatibility, Mn-Si NPs were successfully used for the fluorescence imaging as well as magnetic resonance imaging in vivo.
关键词[WOS]: POT MICROWAVE SYNTHESIS ;  ZEBRAFISH DANIO-RERIO ;  QUANTUM DOTS ;  IN-VIVO ;  MULTIFUNCTIONAL NANOPARTICLES ;  HIGHLY FLUORESCENT ;  PROBES ;  PHOTOLUMINESCENCE ;  NANOCRYSTALS ;  CELLS
语种: 英语
WOS记录号: WOS:000414887000021
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/149702
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Nankai Univ, State Key Lab Med Chem Biol, Tianjin Key Lab Biosensing & Mol Recognit, Coll Chem,Res Ctr Analyt Sci, Tianjin 300071, Peoples R China
2.Nankai Univ, Sch Med, Key Lab Tumor Microenvironm & Neurovasc Regulat, Tianjin 300071, Peoples R China
3.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China

Recommended Citation:
Dou, Ya-Kun,Chen, Yang,He, Xi-Wen,et al. Synthesis of Water-Dispersible Mn2+ Functionalized Silicon Nanoparticles under Room Temperature and Atmospheric Pressure for Fluorescence and Magnetic Resonance Dual-Modality Imaging[J]. ANALYTICAL CHEMISTRY,2017,89(21):11286-11292.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Dou, Ya-Kun]'s Articles
 [Chen, Yang]'s Articles
 [He, Xi-Wen]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Dou, Ya-Kun]‘s Articles
 [Chen, Yang]‘s Articles
 [He, Xi-Wen]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace