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Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane
Yang, Kaiguang1; Liu, Jianhui1,2; Sun, Jingdi3; Zhou, Yuan1; Zhao, Qun1; Li, Senwu1,2; Liu, Lukuan1,2; Zhang, Lihua1; Zhao, Jiuyang3; Zhang, Yukui1
关键词Proteomic Study Complications Of Hemodialysis Dialysis Membrane Ionic Liquid
刊名SCIENCE BULLETIN
2017-09-30
DOI10.1016/j.scib.2017.08.026
62期:18页:1251-1255
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]POLYETHERSULFONE MEMBRANES ; PROTEIN ADSORPTION ; POLYSULFONE
英文摘要The complications of hemodialysis accompanied the hemodialysis and threaten the patients' life. Besides the loss of nutrient substance, such as amino acid and vitamin, we found new clues that the adsorbed proteins on common-used polysulfone-based dialysis membrane might be the reason according to the qualitative proteomic study by ionic liquid assisted sample preparation method. Our results indicated that the adsorbed proteins on the membrane were related with complement activation, blood coagulation, and leukocyte-related biological process. The quantitative proteome further demonstrated some significant changes of signal proteins in the post-dialysis plasma after the hemodialysis, such as beta-2-microglobulin and platelet factor-4, which would further verify these new clues. (C) 2017 Science China Press. Published by Elsevier B.V. and Science China Press. All rights reserved.
语种英语
WOS记录号WOS:000412131000008
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被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/150117
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Peoples R China
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GB/T 7714
Yang, Kaiguang,Liu, Jianhui,Sun, Jingdi,et al. Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane[J]. SCIENCE BULLETIN,2017,62(18):1251-1255.
APA Yang, Kaiguang.,Liu, Jianhui.,Sun, Jingdi.,Zhou, Yuan.,Zhao, Qun.,...&Zhang, Yukui.(2017).Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane.SCIENCE BULLETIN,62(18),1251-1255.
MLA Yang, Kaiguang,et al."Proteomic study provides new clues for complications of hemodialysis caused by dialysis membrane".SCIENCE BULLETIN 62.18(2017):1251-1255.
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