DICP OpenIR
Metabolic profiling analysis of Siraitia grosvenorii revealed different characteristics of green fruit and saccharified yellow fruit
Fang, Chengnan1,2; Wang, Qingqing1,2; Liu, Xinyu1,2; Xu, Guowang1,2
KeywordSiraitia Grosvenorii Uplc-q-tof-ms Metabolic Profiling Saccharification Distribution Characteristics
Source PublicationJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
2017-10-25
DOI10.1016/j.jpba.2017.06.046
Volume145Pages:158-168
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences ; Life Sciences & Biomedicine
WOS SubjectChemistry, Analytical ; Pharmacology & Pharmacy
WOS Research AreaChemistry ; Pharmacology & Pharmacy
WOS KeywordFLIGHT MASS-SPECTROMETRY ; LUO-HAN-GUO ; LIQUID-CHROMATOGRAPHY ; COMPREHENSIVE ANALYSIS ; CHEMICAL-CONSTITUENTS ; MOGROSIDE V ; IN-VITRO ; GLYCOSIDES ; TRITERPENE ; IDENTIFICATION
AbstractSiraitia grosvenorii is an economic and medicinal plant, its fruit is considered to be good to health for its diverse bioactive ingredients. However, the clarification of chemical composition and their changes after saccharification procedure are not well performed. In present study, a metabolomics method based on ultra-high-performance liquid chromatography tandem quadrupole time-of-flight mass spectrometry was developed for metabolic profiling acquisition ofSiraitia grosvenorii extract. Furthermore, information dependent analysis (IDA) combined with self-constructed LC MS/MS identification system for metabolites were employed to identify primary and secondary metabolites in Siraitia grosvenorii. A total of 126 metabolites were identified or tentatively identified. The obvious differences of metabolic profiling between green fruit and saccharified yellow fruit were observed, and metabolites showed their own distribution characteristics in peel, flesh and seed. The majority of the nutrients and effective components were more distributed in flesh and peel, and saccharification was conducive to accumulation of sweet glycosides. This study not only expanded metabolite composition information of Siraitia grosvenorii, but also specified distribution characteristics of identified metabolites. (C) 2017 Elsevier B.V. All rights reserved.
Language英语
WOS IDWOS:000410872200021
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/150139
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Fang, Chengnan,Wang, Qingqing,Liu, Xinyu,et al. Metabolic profiling analysis of Siraitia grosvenorii revealed different characteristics of green fruit and saccharified yellow fruit[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2017,145:158-168.
APA Fang, Chengnan,Wang, Qingqing,Liu, Xinyu,&Xu, Guowang.(2017).Metabolic profiling analysis of Siraitia grosvenorii revealed different characteristics of green fruit and saccharified yellow fruit.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,145,158-168.
MLA Fang, Chengnan,et al."Metabolic profiling analysis of Siraitia grosvenorii revealed different characteristics of green fruit and saccharified yellow fruit".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 145(2017):158-168.
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