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N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry
Cheng, Xina1; Ye, Xueting2; Liu, Dan1; Zhao, Nan1; Gao, Huiyuan2; Wang, Ping1; Ge, Guangbo1; Zhang, Xiaozhe1
刊名RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2017-11-15
DOI10.1002/rcm.7930
31期:21页:1779-1784
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy
关键词[WOS]MALDI-TOF MS ; DESORPTION IONIZATION ; PROTEINS ; METABOLITES
英文摘要Rationale: The matrix plays an essential role in defining detection limits and ionization yields of analytes in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis. Small molecule MALDI-MS analyses commonly suffer from the high background interference generated from matrices. Moreover, the inhomogeneous crystallization of some matrices, such as 2,5-dihydroxybenzoic acid (DHB), is to the detriment of the quality or repeatability of detection. We have found that N-butyl-4-hydroxy-1,8-naphthalimide (BHN) can provide improved performance as a matrix for small molecule analysis.
语种英语
WOS记录号WOS:000412454500001
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/150176
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China
2.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China
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GB/T 7714
Cheng, Xina,Ye, Xueting,Liu, Dan,et al. N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2017,31(21):1779-1784.
APA Cheng, Xina.,Ye, Xueting.,Liu, Dan.,Zhao, Nan.,Gao, Huiyuan.,...&Zhang, Xiaozhe.(2017).N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,31(21),1779-1784.
MLA Cheng, Xina,et al."N-Butyl-4-hydroxy-1,8-naphthalimide: A new matrix for small molecule analysis by matrix-assisted laser desorption/ionization mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 31.21(2017):1779-1784.
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