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题名: Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection
作者: Ma, Xin1;  Liu, Jing2;  Zhang, Zhengxiang1;  Bo, Tao1;  Bai, Yu3;  Liu, Huwei3
刊名: RAPID COMMUNICATIONS IN MASS SPECTROMETRY
发表日期: 2017
DOI: 10.1002/rcm.7767
卷: 31, 期:1, 页:33-38
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences ;  Technology
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical ;  Spectroscopy
英文摘要: RATIONALE: Quadrupole-based tandem mass spectrometry (MS/MS) plays a critical role in 'omics' studies. However, when a particular m/z precursor is selected by the quadrupole, ions other than the precursor are not transmitted through, and the sensitivity and dynamic range thus diminish. Therefore, separation techniques such as ion mobility (IM) are coupled with MS/MS to improve it.
关键词[WOS]: COLLISION CROSS-SECTIONS ;  PARAMETERS ;  PROTEOMICS ;  INSTRUMENTATION ;  MS
语种: 英语
WOS记录号: WOS:000388601300009
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/150345
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Agilent Technol, Beijing 100102, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci,Analyt Chem, Key Lab Bioorgan Chem & Mol Engn,Minist Educ,Inst, Beijing 100871, Peoples R China

Recommended Citation:
Ma, Xin,Liu, Jing,Zhang, Zhengxiang,et al. Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2017,31(1):33-38.
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