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Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection
Ma, Xin1; Liu, Jing2; Zhang, Zhengxiang1; Bo, Tao1; Bai, Yu3; Liu, Huwei3
刊名RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2017
DOI10.1002/rcm.7767
31期:1页:33-38
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
类目[WOS]Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
关键词[WOS]COLLISION CROSS-SECTIONS ; PARAMETERS ; PROTEOMICS ; INSTRUMENTATION ; MS
英文摘要RATIONALE: Quadrupole-based tandem mass spectrometry (MS/MS) plays a critical role in 'omics' studies. However, when a particular m/z precursor is selected by the quadrupole, ions other than the precursor are not transmitted through, and the sensitivity and dynamic range thus diminish. Therefore, separation techniques such as ion mobility (IM) are coupled with MS/MS to improve it.
语种英语
WOS记录号WOS:000388601300009
引用统计
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/150345
专题中国科学院大连化学物理研究所
作者单位1.Agilent Technol, Beijing 100102, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci,Analyt Chem, Key Lab Bioorgan Chem & Mol Engn,Minist Educ,Inst, Beijing 100871, Peoples R China
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Ma, Xin,Liu, Jing,Zhang, Zhengxiang,et al. Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2017,31(1):33-38.
APA Ma, Xin,Liu, Jing,Zhang, Zhengxiang,Bo, Tao,Bai, Yu,&Liu, Huwei.(2017).Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,31(1),33-38.
MLA Ma, Xin,et al."Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 31.1(2017):33-38.
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