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Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection
Ma, Xin1; Liu, Jing2; Zhang, Zhengxiang1; Bo, Tao1; Bai, Yu3; Liu, Huwei3
Source PublicationRAPID COMMUNICATIONS IN MASS SPECTROMETRY
2017
DOI10.1002/rcm.7767
Volume31Issue:1Pages:33-38
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
WOS KeywordCOLLISION CROSS-SECTIONS ; PARAMETERS ; PROTEOMICS ; INSTRUMENTATION ; MS
AbstractRATIONALE: Quadrupole-based tandem mass spectrometry (MS/MS) plays a critical role in 'omics' studies. However, when a particular m/z precursor is selected by the quadrupole, ions other than the precursor are not transmitted through, and the sensitivity and dynamic range thus diminish. Therefore, separation techniques such as ion mobility (IM) are coupled with MS/MS to improve it.
Language英语
WOS IDWOS:000388601300009
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Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/150345
Collection中国科学院大连化学物理研究所
Affiliation1.Agilent Technol, Beijing 100102, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci,Analyt Chem, Key Lab Bioorgan Chem & Mol Engn,Minist Educ,Inst, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Ma, Xin,Liu, Jing,Zhang, Zhengxiang,et al. Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2017,31(1):33-38.
APA Ma, Xin,Liu, Jing,Zhang, Zhengxiang,Bo, Tao,Bai, Yu,&Liu, Huwei.(2017).Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,31(1),33-38.
MLA Ma, Xin,et al."Drift tube ion mobility and four-dimensional molecular feature extraction enable data-independent tandem mass spectrometric 'omics' analysis without quadrupole selection".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 31.1(2017):33-38.
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