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题名: Electrospinning versus microfluidic spinning of functional fibers for biomedical applications
作者: Cheng, Jie1;  Jun, Yesl2;  Qin, Jianhua3;  Lee, Sang-Hoon1, 2, 4
关键词: Electrospinning ;  Microfluidic spinning ;  Tissue engineering ;  Drug delivery ;  Polymer ;  Micro & nano fiber
刊名: BIOMATERIALS
发表日期: 2017
DOI: 10.1016/j.biomaterials.2016.10.040
卷: 114, 页:121-143
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology ;  Technology
类目[WOS]: Engineering, Biomedical ;  Materials Science, Biomaterials
英文摘要: Micro- or nanofiber-based materials have extensive applications in biomedical fields due to their capability to mimic many aspects of physiological microenvironment in vivo. Fabricating micro- or nanofibers using biocompatible and biodegradable materials is becoming of great interest in the area of biomaterials and tissue engineering. Among the various technologies, electrospinning and microfluidic spinning are the two promising approaches to produce fibers at micro- and nano-scale. Choosing an appropriate spinning method is critical important for a specific application. Although some review papers on each spinning method have been published, a review comparing these two methods has not been reported yet. In this review, we present an overview of the two spinning methods including the spinning principle, their unique features and materials selections. Several applications of fibers spun by both methods, especially in tissue engineering, organ function regeneration and drug delivery are introduced. The current challenges, future directions and potential applications of these approaches are discussed as well. (C) 2016 Elsevier Ltd. All rights reserved.
关键词[WOS]: TISSUE-ENGINEERING APPLICATIONS ;  STEM-CELL DIFFERENTIATION ;  BONE INSERTION SITE ;  NANOFIBROUS SCAFFOLDS ;  IN-VIVO ;  COMPOSITE NANOFIBERS ;  ALGINATE FIBERS ;  HYDROGEL FIBERS ;  DRUG-DELIVERY ;  NERVE REGENERATION
语种: 英语
WOS记录号: WOS:000389730000012
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/150443
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Korea Univ, Sch Biomed Engn, Coll Hlth Sci, Seoul 02841, South Korea
2.Korea Univ, KIST Grad Sch Converging Sci & Technol, Seoul 02841, South Korea
3.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China
4.Korea Univ, Coll Hlth Sci, Dept Bioconvergence Engn, Seoul 02841, South Korea

Recommended Citation:
Cheng, Jie,Jun, Yesl,Qin, Jianhua,et al. Electrospinning versus microfluidic spinning of functional fibers for biomedical applications[J]. BIOMATERIALS,2017,114:121-143.
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