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题名: Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs)
作者: Zhang, Xu-Xin1, 2;  Cao, Yun-Feng1, 2, 3, 4;  Wang, Li-Xuan1, 2, 4;  Yuan, Xiao-Lin1;  Fang, Zhong-Ze1, 2, 4, 5
关键词: Enzyme inhibition ;  herb-drug interaction ;  in vitro screening ;  in vitro-in vivo extrapolation (IV-IVE)
刊名: PHARMACEUTICAL BIOLOGY
发表日期: 2017
DOI: 10.3109/13880209.2015.1045621
卷: 55, 期:1, 页:1703-1709
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Plant Sciences ;  Medical Laboratory Technology ;  Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ;  Medical Laboratory Technology ;  Pharmacology & Pharmacy
英文摘要: Contents: Danshen is a popular herb employed to treat cardiovascular and cerebrovascular diseases worldwide. Danshen-drug interaction has not been well studied.
关键词[WOS]: SALVIA-MILTIORRHIZA ;  LIVER-MICROSOMES ;  DANSHEN ;  GLUCURONIDATION ;  WARFARIN ;  PHARMACODYNAMICS ;  PHARMACOKINETICS ;  BIOACTIVATION ;  CONSTITUENTS ;  MEDICINE
语种: 英语
WOS记录号: WOS:000400783300001
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/151976
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Dalian Univ, Affiliated Zhongshan Hosp, Dalian, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Joint Ctr Translat Med, Dalian, Peoples R China
3.Shanghai Inst Planned Parenthood Res, Shanghai Engineer & Technol Res Ctr Reprod Hlth D, Key Lab Contracept & Devices Res NPFPC, Shanghai, Peoples R China
4.Liaoning Med Univ, Affiliated Hosp 1, Dalian, Peoples R China
5.Tianjin Med Univ, Sch Publ Hlth, Dept Toxicol, 22 Qixiangtai Rd, Tianjin 300070, Peoples R China

Recommended Citation:
Zhang, Xu-Xin,Cao, Yun-Feng,Wang, Li-Xuan,et al. Inhibitory effects of tanshinones towards the catalytic activity of UDP-glucuronosyltransferases (UGTs)[J]. PHARMACEUTICAL BIOLOGY,2017,55(1):1703-1709.
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