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Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection
Wu, Lidong1; Lu, Xianbo2; Fu, Xiaochen1; Wu, Lingxia2; Liu, Huan1
Source PublicationSCIENTIFIC REPORTS
2017-07-12
DOI10.1038/s41598-017-05352-7
Volume7
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology
WOS SubjectMultidisciplinary Sciences
WOS Research AreaScience & Technology - Other Topics
WOS KeywordPOLYCHLORINATED-BIPHENYLS PCBS ; BIOSENSOR ; APTAMER ; SURFACE ; CHLORAMPHENICOL ; ATHEROSCLEROSIS ; TOXICITY ; SERUM
AbstractGold nanoparticles (AuNP) dotted reduction graphene oxide (RGO-AuNP) is used as a platform for an aptamer biosensor to selectively detect 3,3'4,4'-polychlorinated biphenyls (PCB77). By anchoring aptamers onto the binding sites of RGO-AuNP and making use of the synergy effect of RGO and AuNP, the RGO-AuNP based biosensor exhibits superior analytical performances to AuNP based biosensor in terms of sensitivity and repeatability. The sensitivity of RGO-AuNP based aptamers (RGO-AuNP-Ap) biosensor (226.8 mu A cm(-2)) is nearly two times higher than that of Au based biosensors (AuNP-Ap/Au electrode, 147.2 mu A cm(-2)). The RGO-AuNP-Ap/Au biosensor demonstrated a linear response for PCB77 concentrations between 1 pg L-1 and 10 mu g L-1, with a low limit of detection (LOD) of 0.1 pg L-1. The superb LOD satisfies the exposure thresholds (uncontaminated water < 0.1 ng L-1) set out by International Agency for Research on Cancer (IARC) and the Environmental Protection Agency (EPA). The proposed biosensor can be a powerful tool for rapid, sensitive and selective detection of PCBs on site.
Language英语
WOS IDWOS:000405423000009
Citation statistics
Cited Times:24[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/152071
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Fishery Sci, Key Lab Control Qual & Safety Aquat Prod, Minisrty Agr, Beijing 100141, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Wu, Lidong,Lu, Xianbo,Fu, Xiaochen,et al. Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection[J]. SCIENTIFIC REPORTS,2017,7.
APA Wu, Lidong,Lu, Xianbo,Fu, Xiaochen,Wu, Lingxia,&Liu, Huan.(2017).Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection.SCIENTIFIC REPORTS,7.
MLA Wu, Lidong,et al."Gold Nanoparticles dotted Reduction Graphene Oxide Nanocomposite Based Electrochemical Aptasensor for Selective, Rapid, Sensitive and Congener-Specific PCB77 Detection".SCIENTIFIC REPORTS 7(2017).
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