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题名: Covalent Probe Finds Carboxylic Acid
作者: Jones, Alexander1, 2;  Zhang, Xiaoyun1, 2;  Lei, Xiaoguang1, 2, 3
刊名: CELL CHEMICAL BIOLOGY
发表日期: 2017-05-18
DOI: 10.1016/j.chembiol.2017.05.003
卷: 24, 页:537-539
收录类别: SCI
文章类型: Editorial Material
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Biochemistry & Molecular Biology
研究领域[WOS]: Biochemistry & Molecular Biology
英文摘要: In this issue of Cell Chemical Biology, Martin-Gago et al. (2017a) disclose a new strategy for the selective covalent targeting of binding site carboxylic acids within the proteome using the isoxazolium salt as a warhead. This discovery paves the way for developing new protein ligation methods as well as covalent drug candidates.
语种: 英语
WOS记录号: WOS:000402418300003
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/152185
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Synthet & Funct Biomol Ctr,Minist Educ, Beijing 100871, Peoples R China
2.Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
3.Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China

Recommended Citation:
Jones, Alexander,Zhang, Xiaoyun,Lei, Xiaoguang. Covalent Probe Finds Carboxylic Acid[J]. CELL CHEMICAL BIOLOGY,2017,24:537-539.
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