中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: The inhibition of UDP-glucuronosyltransferases (UGTs) by vitamin A
作者: Liu, Xin1;  Cao, Yun-Feng2, 3, 4;  Dong, Pei-Pei5;  Zhu, Liang-Liang6;  Zhao, Zhenying7;  Wu, Xue2, 3, 4;  Fu, Zhi-Wei2, 3, 4;  Huang, Chun-Ting2, 3, 4;  Fang, Zhong-Ze7, 8;  Sun, Hong-Zhi1
关键词: Enzyme inhibition ;  UDP-glucuronosyltransferases (UGTs) ;  vitamin A
刊名: XENOBIOTICA
发表日期: 2017
DOI: 10.1080/00498254.2016.1198841
卷: 47, 页:376-381
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Pharmacology & Pharmacy ;  Toxicology
研究领域[WOS]: Pharmacology & Pharmacy ;  Toxicology
英文摘要: The exposed level of vitamin A in plasma might be exceeded due to the both inadvertent and clinical utilization. The adverse effects of vitamin A have been frequently reported, however, the mechanism remains unclear. The inhibition of vitamin A on the activity of UDP-glucuronosyltransferases (UGTs) was determined using in vitro incubation system to explain the adverse effects of vitamin A from a new perspective.
关键词[WOS]: DRUG-METABOLISM ;  RETINOIC ACID ;  SUBSTRATE ;  EXPRESSION ;  UGT2B7 ;  2B7 ;  HYPERBILIRUBINEMIA ;  PHARMACOKINETICS ;  SELECTIVITY ;  ISOFORMS
语种: 英语
WOS记录号: WOS:000399497600003
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/152330
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Liaoning Med Univ, Affiliated Hosp 1, Jinzhou, Liaoning, Peoples R China
2.RSKT Biopharma Inc, Dalian, Liaoning, Peoples R China
3.Chinese Acad Sci, Joint Ctr Translat Med, Dalian Inst Chem Phys, Dalian, Peoples R China
4.Liaoning Med Univ, Affiliated Hosp 1, Dalian, Peoples R China
5.Dalian Med Univ, Inst Integrat Med, Dalian, Peoples R China
6.Anqing Normal Univ, Sch Life Sci, Dept Food Sci & Technol, Anqing, Peoples R China
7.Tianjin Union Med Ctr, Tianjin, Peoples R China
8.Tianjin Med Univ, Sch Publ Hlth, Dept Toxicol, Tianjin, Peoples R China

Recommended Citation:
Liu, Xin,Cao, Yun-Feng,Dong, Pei-Pei,et al. The inhibition of UDP-glucuronosyltransferases (UGTs) by vitamin A[J]. XENOBIOTICA,2017,47:376-381.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Liu, Xin]'s Articles
 [Cao, Yun-Feng]'s Articles
 [Dong, Pei-Pei]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Liu, Xin]‘s Articles
 [Cao, Yun-Feng]‘s Articles
 [Dong, Pei-Pei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace