DICP OpenIR
Glycerolipid remodeling triggered by phosphorous starvation and recovery in Nannochloropsis oceanica
Meng, Yingying1,2; Cao, Xupeng2; Yang, Miao2; Liu, Jiao2,3; Yao, Changhong4; Xue, Song2
Corresponding AuthorXue, Song(xuesong@dicp.ac.cn)
KeywordGlycerolipid remodeling Lipidomic analysis Phosphorous limitation and recovery Nannochloropsis oceanica DGTS
Source PublicationALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
2019-05-01
ISSN2211-9264
DOI10.1016/j.algal.2019.101451
Volume39Pages:9
Funding ProjectChina Postdoctoral Science Foundation[2018M632709] ; National High-tech R&D Program (863 Program)[2012AA052101]
Funding OrganizationChina Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program) ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program) ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program) ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program)
WOS SubjectBiotechnology & Applied Microbiology
WOS Research AreaBiotechnology & Applied Microbiology
WOS KeywordMICROALGA TETRASELMIS-SUBCORDIFORMIS ; FATTY-ACID-COMPOSITION ; CHLAMYDOMONAS-REINHARDTII ; PHOSPHATE STARVATION ; NITROGEN DEPRIVATION ; STARCH PRODUCTION ; ACCUMULATION ; LIPIDS ; TRIACYLGLYCEROL ; BIOSYNTHESIS
AbstractTo understand the function of DGTS (diacylglyceryl-N,N,N-trimethyl-homoserine) as substitution of PC (phosphatidylcholine), Nannochloropsis oceanica has been chosen as the model system because it has DGTS and PC simultaneously. Phosphorus is a regulator for DGTS and PC. Generally, DGTS increases and correspondingly PC decreases under phosphorous starvation. However, the function of DGTS and its fatty acid origin under phosphorous starvation, and the resurgence of PC triggered by phosphorus recovery remain not clarified completely. In the present study, we investigated the effect of phosphorus starvation and recovery on polar glycerolipid remodeling in N. oceanica based on quantitative lipidomic data. Through targeted lipidomics analysis, we proposed that, under phosphorus deprivation, DGTS serves as the central intermediate in glycerolipid remodeling via acting as the carrier of the C18 fatty acids desaturation by replacement of PC, maintaining the biosynthesis of EPA (eicosapentaenoic acid) and providing the EPA acyl as a precursor for formation of chloroplast glycolipids. The prokaryotic molecular species of DGTS are mainly from de novo biosynthesis pathway and make the major contribution for the DGTS increase. In the process of resupplying phosphorus, PC increased attributing to hydrolysis of TAG, generating diacylglycerol for PC biosynthesis. These new information demonstrated that DGTS and PC varied conversely in different metabolic pathways as revealed by targeted lipidomic data.
Language英语
Funding OrganizationChina Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program) ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program) ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program) ; China Postdoctoral Science Foundation ; China Postdoctoral Science Foundation ; National High-tech R&D Program (863 Program) ; National High-tech R&D Program (863 Program)
WOS IDWOS:000467066000029
PublisherELSEVIER SCIENCE BV
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/165465
Collection中国科学院大连化学物理研究所
Corresponding AuthorXue, Song
Affiliation1.Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Jinan 250014, Shandong, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Marine Bioengn Grp, Dalian 116023, Peoples R China
3.Qilu Univ Technol, Dept Bioengn, Jinan 250353, Shandong, Peoples R China
4.Sichuan Univ, Sch Chem Engn, Dept Pharmaceut & Biol Engn, Chengdu 610065, Sichuan, Peoples R China
Recommended Citation
GB/T 7714
Meng, Yingying,Cao, Xupeng,Yang, Miao,et al. Glycerolipid remodeling triggered by phosphorous starvation and recovery in Nannochloropsis oceanica[J]. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,2019,39:9.
APA Meng, Yingying,Cao, Xupeng,Yang, Miao,Liu, Jiao,Yao, Changhong,&Xue, Song.(2019).Glycerolipid remodeling triggered by phosphorous starvation and recovery in Nannochloropsis oceanica.ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS,39,9.
MLA Meng, Yingying,et al."Glycerolipid remodeling triggered by phosphorous starvation and recovery in Nannochloropsis oceanica".ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS 39(2019):9.
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