DICP OpenIR
Cell-imprinted polydimethylsiloxane for the selective cell adhesion
Liu, Lukuan1,2,3; Yang, Kaiguang2; Dai, Zhongpeng2; Liang, Zhen2; Zhang, Lihua2; Peng, Xiaojun1; Zhang, Yukui2
Corresponding AuthorZhang, Lihua(lihuazhang@dicp.ac.cn)
KeywordCell adhesion Aptamer Cell imprinting Hierarchical structures Click chemistry
Source PublicationCHINESE CHEMICAL LETTERS
2019-03-01
ISSN1001-8417
DOI10.1016/j.cclet.2018.11.006
Volume30Issue:3Pages:672-675
Funding ProjectNational Key Research and Development Program[2016YFA0501401] ; National Natural Science Foundation of China[21575143] ; National Natural Science Foundation of China[91543201] ; CAS Key Project in Frontier Science[QYZDY-SSW-SLH017]
Funding OrganizationNational Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science
WOS SubjectChemistry, Multidisciplinary
WOS Research AreaChemistry
WOS KeywordCANCER-CELLS ; APTAMER ; RECOGNITION ; CAPTURE
AbstractCell adhesion is the basis for some cell isolation methods, and is influenced by both of the biochemical and topographic characteristics of the substrates. Herein, based on cell imprinting and click chemistry, we have developed a cell-imprinted polydimethylsiloxane (PDMS) with aptamer functionalization (APT-CIS). The atom force microscopic analysis results showed that the hierarchical structure matching well with the target cells is successfully introduced on the surface of the APT-CIS. By using the synergistic effects of hierarchical structure and aptamer affinity, the APT-CIS was successfully used for the selective cell adhesion, and 93.9% +/- 0.8% of the captured cells could then be released. Thus, the APT-CIS holds promise in selective cell isolation and sorting fields. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
Language英语
Funding OrganizationNational Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science
WOS IDWOS:000462106900031
PublisherELSEVIER SCIENCE INC
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/165743
Collection中国科学院大连化学物理研究所
Corresponding AuthorZhang, Lihua
Affiliation1.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Liu, Lukuan,Yang, Kaiguang,Dai, Zhongpeng,et al. Cell-imprinted polydimethylsiloxane for the selective cell adhesion[J]. CHINESE CHEMICAL LETTERS,2019,30(3):672-675.
APA Liu, Lukuan.,Yang, Kaiguang.,Dai, Zhongpeng.,Liang, Zhen.,Zhang, Lihua.,...&Zhang, Yukui.(2019).Cell-imprinted polydimethylsiloxane for the selective cell adhesion.CHINESE CHEMICAL LETTERS,30(3),672-675.
MLA Liu, Lukuan,et al."Cell-imprinted polydimethylsiloxane for the selective cell adhesion".CHINESE CHEMICAL LETTERS 30.3(2019):672-675.
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