DICP OpenIR
A ratiometric time-gated luminescence probe for hydrogen sulfide based on copper(II)-coupled lanthanide complexes
Tang, Zhixin1; Song, Bo1; Ma, Hua1; Shi, Yuanyuan2; Yuan, Jingli1
Corresponding AuthorSong, Bo(bo.song@dlut.edu.cn) ; Yuan, Jingli(jlyuan@dlut.edu.cn)
KeywordLanthanide complex Time-gated luminescence Hydrogen sulfide Ratiometric luminescence probe Bioimaging
Source PublicationANALYTICA CHIMICA ACTA
2019-02-21
ISSN0003-2670
DOI10.1016/j.aca.2018.10.048
Volume1049Pages:152-160
Funding ProjectNational Natural Science Foundation of China[21477011] ; National Natural Science Foundation of China[21775015] ; National Natural Science Foundation of China[21475016]
Funding OrganizationNational Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordFLUORESCENT-PROBE ; CELLS ; SULFUR ; ROLES ; ASSAY ; H2S
AbstractTime-gated luminescence (TGL) bioassay technique using luminescent lanthanide complexes as probes has exhibited excellent practicability in detection of various analytes in autofluorescence-rich biosamples. Herein, a novel copper(II)-coupled lanthanide complex-based luminescence probe has been developed for the ratiometric TGL detection of hydrogen sulfide (H2S) in vitro and in vivo. The probe is constructed based on a dual-functional ligand that was synthesized by conjugating di(2-picolyl)amine with terpyridine polyacid (DATP) using the "click chemistry" method. The as-prepared ligand can coordinate to Eu3+ and Tb3+ ions with its terpyridine polyacid moiety to display long-lived emissions of Eu3+ and Tb3+ ions, while the further coordination of its di(2-picolyl)amino moiety to Cu2+ induces to the luminescence quenching of the Eu3+ complexes, which allows the probe consisting of the heterometallic Cu2+-DATP-Eu3+/Tb3+ complexes to be constructed. After the probe was reacted with H2S to lead to the release of Cu2+ from the complexes, the emission of Eu3+ at 610 nm was remarkably enhanced, while that of Tb3+ at 540 nm was changed slightly. This luminescence response feature allowed the probe to be conveniently applied for the ratiometric TGL determination of H2S with I-610/I-540 as the signal. The applicability of the probe for quantitative detection of H2S in human sera as well as for imaging of H2S in living cells and zebrafish were evaluated. All of the results proved the potential of the probe for in vitro and in vivo applications. (C) 2018 Elsevier B.V. All rights reserved.
Language英语
Funding OrganizationNational Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS IDWOS:000454789100017
PublisherELSEVIER SCIENCE BV
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/166341
Collection中国科学院大连化学物理研究所
Corresponding AuthorSong, Bo; Yuan, Jingli
Affiliation1.Dalian Univ Technol, Sch Chem, State Key Lab Fine Chem, Dalian 116024, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Gold Catalysis Res Ctr, Dalian 116023, Peoples R China
Recommended Citation
GB/T 7714
Tang, Zhixin,Song, Bo,Ma, Hua,et al. A ratiometric time-gated luminescence probe for hydrogen sulfide based on copper(II)-coupled lanthanide complexes[J]. ANALYTICA CHIMICA ACTA,2019,1049:152-160.
APA Tang, Zhixin,Song, Bo,Ma, Hua,Shi, Yuanyuan,&Yuan, Jingli.(2019).A ratiometric time-gated luminescence probe for hydrogen sulfide based on copper(II)-coupled lanthanide complexes.ANALYTICA CHIMICA ACTA,1049,152-160.
MLA Tang, Zhixin,et al."A ratiometric time-gated luminescence probe for hydrogen sulfide based on copper(II)-coupled lanthanide complexes".ANALYTICA CHIMICA ACTA 1049(2019):152-160.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Tang, Zhixin]'s Articles
[Song, Bo]'s Articles
[Ma, Hua]'s Articles
Baidu academic
Similar articles in Baidu academic
[Tang, Zhixin]'s Articles
[Song, Bo]'s Articles
[Ma, Hua]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Tang, Zhixin]'s Articles
[Song, Bo]'s Articles
[Ma, Hua]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.