DICP OpenIR
Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry
Li, Lingdong1; Zhang, Fengxiang1; Gai, Fangyuan2; Zhou, Hao3; Chi, Xiaofang; Wang, Hande1; Zhao (Kent), Zongbao4
Corresponding AuthorLi, Lingdong(lild@dlut.edu.cn)
KeywordN-chloramine antibacterial agents organic synthesis perfluorophenyl azide chemistry polyurethane surface modification
Source PublicationCANADIAN JOURNAL OF CHEMISTRY
2018-10-01
ISSN0008-4042
DOI10.1139/cjc-2018-0156
Volume96Issue:10Pages:939-948
Funding ProjectFundamental Research Funds for the Central Universities[DUT14RC(3)081] ; Fundamental Research Funds for the Central Universities[DUT17LK17] ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation[21501018]
Funding OrganizationFundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation
WOS SubjectChemistry, Multidisciplinary
WOS Research AreaChemistry
WOS KeywordQUATERNARY AMMONIUM MOIETIES ; HALAMINE POLYMERIC BIOCIDES ; ANTIBACTERIAL ACTIVITY ; STAPHYLOCOCCUS-AUREUS ; POLY(ETHYLENE-TEREPHTHALATE) ; COTTON ; FUNCTIONALIZATION ; NANOPARTICLES ; DISINFECTION ; FABRICATION
AbstractTo control the pathogen cross contaminations on medical material surface, there is a pressing need to develop antimicrobial materials with highly efficacious surface biocidal activity. In this work, N-chloramine precursors containing a quaternary ammonium unit and perfluorophenyl azide unit were synthesized and covalently immobilized on inert polyurethane (PU) film upon UV light irradiation. The surface modification was confirmed by contact angle, Fourier transform infrared (ATR FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and atomic force microscopy (AFM) analyses. After bleaching treatment, satisfactory biocidal activity was achieved for the surface-modified PU films. It was found that the introduced surface QA center contributed an even faster surface contact killing behavior and that precursors with a longer structural linker caused higher surface chlorine content and higher antimicrobial efficacy. This approach provides a novel and facile method that enables the covalent immobilization of N-chloramine precursors on inert polymeric surface to produce durable antimicrobial materials.
Language英语
Funding OrganizationFundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation ; Fundamental Research Funds for the Central Universities ; Fundamental Research Funds for the Central Universities ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry ; Chinese National Natural Science Foundation ; Chinese National Natural Science Foundation
WOS IDWOS:000445699400007
PublisherCANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
Citation statistics
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/166999
Collection中国科学院大连化学物理研究所
Corresponding AuthorLi, Lingdong
Affiliation1.Dalian Univ Technol, State Key Lab Fine Chem, Sch Petr & Chem Engn, 2 Dagong Rd, Panjin 124221, Peoples R China
2.Changchun Univ Technol, Jilin Prov Key Lab Carbon Fiber Dev & Applicat, Coll Chem & Life Sci, Changchun 130012, Jilin, Peoples R China
3.Dalian Univ Technol, Sch Food & Environm, 2 Dagong Rd, Panjin 124221, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian, Peoples R China
Recommended Citation
GB/T 7714
Li, Lingdong,Zhang, Fengxiang,Gai, Fangyuan,et al. Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry[J]. CANADIAN JOURNAL OF CHEMISTRY,2018,96(10):939-948.
APA Li, Lingdong.,Zhang, Fengxiang.,Gai, Fangyuan.,Zhou, Hao.,Chi, Xiaofang.,...&Zhao .(2018).Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry.CANADIAN JOURNAL OF CHEMISTRY,96(10),939-948.
MLA Li, Lingdong,et al."Novel N-chloramine precursors for antimicrobial application: synthesis and facile covalent immobilization on polyurethane surface based on perfluorophenyl azide (PFPA) chemistry".CANADIAN JOURNAL OF CHEMISTRY 96.10(2018):939-948.
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