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题名: Study on bioactivity of extracts from marine sponges in Chinese Sea
作者: Xue, S;  Zhang, HT;  Wu, PC;  Zhang, W;  Yuan, Q
关键词: Hymeniacidon perleve ;  Reniochalina sp. ;  Acanthella acuta Schmidt ;  bioactivity screening
刊名: JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY
发表日期: 2004-01-07
DOI: 10.1016/j.jembe.2003.08.004
卷: 298, 期:1, 页:71-78
收录类别: SCI
文章类型: Article
项目归属: 1812
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Ecology ;  Marine & Freshwater Biology
研究领域[WOS]: Environmental Sciences & Ecology ;  Marine & Freshwater Biology
英文摘要: The bioactivity screening of fractions from two inter-tidal sponges collected from the north of China Yellow Sea and one sponge collected from the South Chinese Sea was reported in this study. In sponge Hymeniacidon perleve there were 9 fractions out of 15 from CHCl3 extract with anti Staphylococcus aureus activity, 9 fractions out of 19 from BuOH extract with anti Escherichia coli activity, and three fractions from CHCl3 extract which had moderate to strong activity in inhibiting Bacillus subtilis, Candida albicans, and Aspergilus niger. The fractions of Reniochalina sp. showed bioactivity against bacteria and fungi. The fractions of Acanthella acuta Schmidt showed bioactivity against S. aureus and fungi. One compound from H. perleve obtained by the bioactively directing isolation was tested for bioactivity against the human hepatoma cell line Qgy7701 (IC50 10.1 mug/ml), Burkitt's lymphoma cell line Raji (IC50 9.76 mug/ml) and chronic myelogenous leukemia K562 (IC50 1.90 mug/ml). (C) 2003 Elsevier B.V. All rights reserved.
关键词[WOS]: NATURAL-PRODUCTS ;  ANTITUMOR
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000188203400005
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/81155
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Marine Bioprod Engn Grp, Dalian 116023, Peoples R China
2.Flinders Univ S Australia, CRC Bioprod, Bedford Pk, SA 5042, Australia
3.Flinders Univ S Australia, Dept Med Biotechnol, Adelaide, SA 5042, Australia

Recommended Citation:
Xue, S,Zhang, HT,Wu, PC,et al. Study on bioactivity of extracts from marine sponges in Chinese Sea[J]. JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY,2004,298(1):71-78.
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