中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles
作者: Yang, J;  Xu, GW;  Hong, QF;  Liebich, HM;  Lutz, K;  Schmulling, RM;  Wahl, HG
关键词: pattern recognition ;  diabetes mellitus ;  fatty acid profiles ;  linear discriminant analysis ;  artificial neural networks ;  metabonomics
刊名: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
发表日期: 2004-12-25
DOI: 10.1016/j.jchromb.2004.09.023
卷: 813, 期:1-2, 页:53-58
收录类别: SCI
文章类型: Article
项目归属: 1808
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: Metabonomics, the study of metabolites and their roles in various disease states, is a novel methodology arising from the post-genomics era. This methodology has been applied in many fields, including work in cardiovascular research and drug toxicology. In this study, metabonomics method was employed to the diagnosis of Type 2 diabetes mellitus (DM2) based on serum lipid metabolites. The results suggested that serum fatty acid profiles determined by capillary gas chromatography combined with pattern recognition analysis of the data might provide an effective approach to the discrimination of Type 2 diabetic patients from healthy controls. And the applications of pattern recognition methods have improved the sensitivity and specificity greatly. (C) 2004 Elsevier B.V. All rights reserved.
关键词[WOS]: FUNCTIONAL GENOMICS ;  NEURAL NETWORKS ;  MELLITUS ;  LIPIDS
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000225413200005
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/81603
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2004AF3GJ63D2O.pdf(125KB)----开放获取--View Download

作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&D Ctr, Dalian 116011, Peoples R China
2.Univ Tubingen, Med Klin, Zent Lab, D-72076 Tubingen, Germany
3.Klinikum FUlda, Inst Lab Med, D-36043 Fulda, Germany

Recommended Citation:
Yang, J,Xu, GW,Hong, QF,et al. Discrimination of Type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles[J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,2004,813(1-2):53-58.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Yang, J]'s Articles
 [Xu, GW]'s Articles
 [Hong, QF]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Yang, J]‘s Articles
 [Xu, GW]‘s Articles
 [Hong, QF]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 2004AF3GJ63D2O.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace