中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Separation of acidic and basic compounds in capillary electrochromatography with polymethacrylate-based monolithic columns
作者: Ping, GC;  Zhang, LH;  Zhang, L;  Zhang, WB;  Schmitt-Kopplin, P;  Kettrup, A;  Zhang, YK
关键词: electrochromatography ;  monolithic columns ;  stationary phases ;  electrochromatography
刊名: JOURNAL OF CHROMATOGRAPHY A
发表日期: 2004-05-07
DOI: 10.1016/j.chroma.2004.02.063
卷: 1035, 期:2, 页:265-270
收录类别: SCI
文章类型: Article
项目归属: 1810
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: Methacrylate-based monolithic columns with electroosmotic flow (EOF) or very weak EOF are prepared by in situ copolymerization in the presence of a porogen in fused-silica capillaries pretreated with a bifunctional reagent. Satisfactory separations of acidic and basic compounds on the column with EOF at either low or high pH are achieved, respectively. With sulfonic groups as dissociation functionalities, sufficient EOF mobility still remains as high as 1.74 x 10(-4) cm(2) s(-1) V-1 at low pH. Under this condition, seven acidic compounds are readily separated within 5.7 min. Moreover, at high pH, the peak shape of basic compounds is satisfactory without addition of any masking amines into running mobile phase since the secondary interaction between the basic compounds and the monolithic stationary phase are minimized at high pH. Reversed-phase mechanism for both acidic and basic compounds is observed under investigated separation conditions. In addition, possibilities of acidic and basic compound separations on a monolithic column with extremely low EOF are discussed. (C) 2004 Elsevier B.V. All rights reserved.
关键词[WOS]: PHASE LIQUID-CHROMATOGRAPHY ;  RIGID POLYMER MONOLITHS ;  REVERSED-PHASE ;  STATIONARY PHASES ;  CONTINUOUS BEDS ;  PACKED-COLUMNS ;  PERFORMANCE ;  MEDIA ;  NUCLEOSIDES ;  FLOW
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000220783100012
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/81647
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
200415811P7555.pdf(102KB)----开放获取--View Download

作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China
2.GSF Natl Ctr Environm & Hlth, Inst Ecol Chem, D-85764 Neuherberg, Germany

Recommended Citation:
Ping, GC,Zhang, LH,Zhang, L,et al. Separation of acidic and basic compounds in capillary electrochromatography with polymethacrylate-based monolithic columns[J]. JOURNAL OF CHROMATOGRAPHY A,2004,1035(2):265-270.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Ping, GC]'s Articles
 [Zhang, LH]'s Articles
 [Zhang, L]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Ping, GC]‘s Articles
 [Zhang, LH]‘s Articles
 [Zhang, L]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 200415811P7555.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace