DICP OpenIR
Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines
Huang, XD; Kong, LA; Li, X; Chen, XG; Guo, M; Zou, HF
KeywordReviews Screening Bioactive Compounds
Source PublicationJOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
2004-12-05
DOI10.1016/j.jchromb.2004.06.046
Volume812Issue:1-2Pages:71-84
Indexed BySCI
SubtypeReview
Funding Project1809
Contribution Rank1;1
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS KeywordHUMAN SERUM-ALBUMIN ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; BIOLOGICALLY-ACTIVE COMPOUNDS ; PHARMACOLOGICAL TESTING METHOD ; AFFINITY-CHROMATOGRAPHY ; STATIONARY-PHASE ; BIOMEMBRANE CHROMATOGRAPHY ; MOLECULAR BIOCHROMATOGRAPHY ; ANGELICA-SINENSIS ; HERBAL MEDICINES
AbstractTraditional Chinese medicines (TCMs), due to their long time clinic test and reliable therapeutic efficacy, are attracting increased global attention served as excellent pools of bioactive compounds for the discovery of new drugs. However, hundreds or even thousands of components are usually contained in traditional Chinese medicines and only a few compounds are responsible for the pharmaceutical and/or toxic effects. The large numbers of other components in traditional Chinese medicines make the screening and analysis of the bioactive components extremely difficult. By the way, the combination effect of bioactive components on the pharmacological activity makes it very difficult to clear the therapeutic mechanism of TCMs. Therefore, some strategies have to design for screening of bioactive compounds in traditional Chinese medicines, which further leads to disclose the therapeutic mechanism of TCMs in molecular level. The review will summarize the present state of the art of screening strategy for active compounds in traditional Chinese medicines, and the chromatography methods for screening and analysis of bioactive compounds in traditional Chinese medicines will be emphasized. (C) 2004 Elsevier B.V. All rights reserved.
Language英语
URL查看原文
WOS IDWOS:000225410300006
Citation statistics
Cited Times:118[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/81991
Collection中国科学院大连化学物理研究所
AffiliationChinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China
Recommended Citation
GB/T 7714
Huang, XD,Kong, LA,Li, X,et al. Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines[J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,2004,812(1-2):71-84.
APA Huang, XD,Kong, LA,Li, X,Chen, XG,Guo, M,&Zou, HF.(2004).Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,812(1-2),71-84.
MLA Huang, XD,et al."Strategy for analysis and screening of bioactive compounds in traditional Chinese medicines".JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 812.1-2(2004):71-84.
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