DICP OpenIR
The study on a PVC membrane electrode for gemfibrozil
Xu, F; Sun, LX; Matsuda, N; Okada, T; Tan, ZC; Liang, JG
关键词Gemfibrozil Ion Selective Electrode Orthogonal Experimental Design Quantitative Determination
刊名BIOLOGICAL & PHARMACEUTICAL BULLETIN
2002-02-01
25期:2页:165-167
收录类别SCI
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]CHROMATOGRAPHIC DETERMINATION ; PLASMA ; METABOLITES ; URINE
英文摘要In this paper, a poly(vinyl chloride) (PVC) membrane electrode is prepared for gemfibrozil, 2, 2-dimethyl-5(2,5-xylyloxy) valeric acid, based on its ion pair complexes with hexadecyltrioctyl ammonium iodide (HTOA). The membrane composition of the electrode was optimized by using the sequential level elimination method for orthogonal experimental design. The electrode has a Nernstian response range from 2.5 X 10(-5) to 0.1 mol/l with an average slope of 55.3 mV/decade. The limit of detection is 7.1 X 10(-6) mol/l. The electrode responses were not affected by pH in the range 10.0-12.3. A Na2B4O7-Na2CO3 buffer of pH = 11.0 was selected as the background electrolyte solution for potentiometric measurements. The electrode was used for determining gemfibrozil in pharmaceutical preparations with satisfactory results.
语种英语
原文出处查看原文
WOS记录号WOS:000173615100002
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/83165
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Jinan Univ, Dept Chem, Guangzhou 510632, Peoples R China
3.Natl Inst Adv Ind Sci & Technol, Nanoarchitecton Res Ctr, Tsukuba, Ibaraki 3058565, Japan
4.Natl Inst Adv Ind Sci & Technol, Electrochem Energy Conver Lab, Tsukuba, Ibaraki 3058565, Japan
5.Human Inst Drug Detect, Changsha 410001, Peoples R China
推荐引用方式
GB/T 7714
Xu, F,Sun, LX,Matsuda, N,et al. The study on a PVC membrane electrode for gemfibrozil[J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN,2002,25(2):165-167.
APA Xu, F,Sun, LX,Matsuda, N,Okada, T,Tan, ZC,&Liang, JG.(2002).The study on a PVC membrane electrode for gemfibrozil.BIOLOGICAL & PHARMACEUTICAL BULLETIN,25(2),165-167.
MLA Xu, F,et al."The study on a PVC membrane electrode for gemfibrozil".BIOLOGICAL & PHARMACEUTICAL BULLETIN 25.2(2002):165-167.
条目包含的文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
20026NC79A370F.pdf(43KB) 开放获取--请求全文
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Xu, F]的文章
[Sun, LX]的文章
[Matsuda, N]的文章
百度学术
百度学术中相似的文章
[Xu, F]的文章
[Sun, LX]的文章
[Matsuda, N]的文章
必应学术
必应学术中相似的文章
[Xu, F]的文章
[Sun, LX]的文章
[Matsuda, N]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。