DICP OpenIR
Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data
Shan, YC; Zhao, RH; Xu, GW; Liebich, HM; Zhang, YK
KeywordClassification Cancer Nucleosides Probabilistic Neural Network
Source PublicationANALYTICA CHIMICA ACTA
2002-10-23
Volume471Issue:1Pages:77-86
Indexed BySCI
SubtypeArticle
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordMASS-SPECTROMETRY ; MODIFIED NUCLEOSIDES ; PATTERN-RECOGNITION ; RETENTION BEHAVIOR ; SENSOR ARRAY ; IDENTIFICATION ; CLASSIFICATION ; CHROMATOGRAPHY ; CLASSIFIERS ; TOOL
AbstractAs a recently developed and powerful classification tool, probabilistic neural network was used to distinguish cancer patients from healthy persons according to the levels of nucleosides in human urine. Two datasets (containing 32 and 50 patterns, respectively) were investigated and the total consistency rate obtained was 100% for dataset 1 and 94% for dataset 2. To evaluate the performance of probabilistic neural network, linear discriminant analysis and learning vector quantization network, were also applied to the classification problem. The results showed that the predictive ability of the probabilistic neural network is stronger than the others in this study. Moreover, the recognition rate for dataset 2 can achieve to 100% if combining, these three methods together, which indicated the promising potential of clinical diagnosis by combining different methods. (C) 2002 Elsevier Science B.V. All rights reserved.
Language英语
URL查看原文
WOS IDWOS:000178565700008
Citation statistics
Cited Times:34[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/83249
Collection中国科学院大连化学物理研究所
Affiliation1.Acad Sinica, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
2.Univ Tubingen, Med Klin, D-72076 Tubingen, Germany
Recommended Citation
GB/T 7714
Shan, YC,Zhao, RH,Xu, GW,et al. Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data[J]. ANALYTICA CHIMICA ACTA,2002,471(1):77-86.
APA Shan, YC,Zhao, RH,Xu, GW,Liebich, HM,&Zhang, YK.(2002).Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data.ANALYTICA CHIMICA ACTA,471(1),77-86.
MLA Shan, YC,et al."Application of probabilistic neural network in the clinical diagnosis of cancers based on clinical chemistry data".ANALYTICA CHIMICA ACTA 471.1(2002):77-86.
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