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题名: Melatonin in Chinese medicinal herbs
作者: Chen, GF;  Huo, YS;  Tan, DX;  Liang, Z;  Zhang, WB;  Zhang, YK
关键词: melatonin ;  plant ;  herbs ;  antioxidant ;  HPLC ;  MS
刊名: LIFE SCIENCES
发表日期: 2003-05-23
DOI: 10.1016/S0024-3205(03)00252-2
卷: 73, 期:1, 页:19-26
收录类别: SCI
文章类型: Article
部门归属: 1810
项目归属: 1810
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine
类目[WOS]: Medicine, Research & Experimental ;  Pharmacology & Pharmacy
研究领域[WOS]: Research & Experimental Medicine ;  Pharmacology & Pharmacy
英文摘要: Melatonin is a highly conserved molecule that not only exists in animals, but also is present in bacteria, unicellular organisms and in plants. Since melatonin is an antioxidant, in plants melatonin was speculated to protect them from intrinsic and environmental oxidative stress. More importantly, melatonin in edible plants inevitably enters animals and human through feed and food. In this study, more than 100 Chinese medicinal herbs were analyzed using the methods of solid phase extraction and HPLC-FD on-line with MS to determine whether melatonin is present in these commonly used herbs. Melatonin was detected in majority of these plants. Sixty-four of them contain melatonin in excess of 10 ng per gram dry mass. Melatonin levels in several herbs are in excess of 1000 ng/g. It is well known that normal average physiological plasma levels of melatonin are only 10-60 pg/mL. These high level-melatonin containing plants are traditionally used to treat diseases which presumably involve free radical damage. The current study provides new information concerning one potentially effective constituent present in a large number of medicinal herbs. The results suggest that these herbs should be reevaluated in reference to their nutritional and medicinal value. (C) 2003 Elsevier Science Inc. All rights reserved.
关键词[WOS]: EDIBLE PLANTS ;  PINEAL MELATONIN ;  ANTIOXIDANT ;  PROTECTION ;  DISEASE ;  SYSTEM ;  SERUM
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000182775600002
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/83439
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem & Phys, Dalian 116011, Peoples R China
2.Univ Texas, Hlth Sci Ctr, Dept Microbiol, San Antonio, TX 78284 USA
3.Univ Texas, Hlth Sci Ctr, Dept Cellular & Struct Biol, San Antonio, TX 78284 USA

Recommended Citation:
Chen, GF,Huo, YS,Tan, DX,et al. Melatonin in Chinese medicinal herbs[J]. LIFE SCIENCES,2003,73(1):19-26.
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