DICP OpenIR
Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method
Xu, G; Schmid, HR; Lu, X; Liebich, HM; Lu, P
Source PublicationBIOMEDICAL CHROMATOGRAPHY
2000-11-01
Volume14Issue:7Pages:459-463
Indexed BySCI
SubtypeArticle
Department4
Funding Project402
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
WOS SubjectBiochemical Research Methods ; Biochemistry & Molecular Biology ; Chemistry, Analytical ; Pharmacology & Pharmacy
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
WOS KeywordCAPILLARY-ELECTROPHORESIS ; PSEUDOURIDINE ; CARCINOMA ; PROTEIN ; MARKERS
AbstractModified nucleosides, formed post-transcriptionally in RNA by a number of modification enzymes, are excreted in abnormal levels in the urine of patients with malignant tumors. To test their usefulness as tumor markers, and to compare them with the conventional tumor markers, a reversed-phase high-performance liquid chromatographic (RP-HPLC) method and a factor analysis method have been used to study the excretion pattern of nucleosides of breast cancer patients. A clear cut differentiation of the breast cancer group and the healthy individuals in two clusters without overlapping was obtained. Copyright (C) 2000 John Wiley & Sons, Ltd.
Language英语
URL查看原文
WOS IDWOS:000165458200002
Citation statistics
Cited Times:45[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/84029
Collection中国科学院大连化学物理研究所
Affiliation1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
2.Med Univ Klin, D-72076 Tubingen, Germany
Recommended Citation
GB/T 7714
Xu, G,Schmid, HR,Lu, X,et al. Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method[J]. BIOMEDICAL CHROMATOGRAPHY,2000,14(7):459-463.
APA Xu, G,Schmid, HR,Lu, X,Liebich, HM,&Lu, P.(2000).Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method.BIOMEDICAL CHROMATOGRAPHY,14(7),459-463.
MLA Xu, G,et al."Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method".BIOMEDICAL CHROMATOGRAPHY 14.7(2000):459-463.
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