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Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method
Xu, G; Schmid, HR; Lu, X; Liebich, HM; Lu, P
刊名BIOMEDICAL CHROMATOGRAPHY
2000-11-01
14期:7页:459-463
收录类别SCI
文章类型Article
部门归属4
项目归属402
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]Biochemical Research Methods ; Biochemistry & Molecular Biology ; Chemistry, Analytical ; Pharmacology & Pharmacy
研究领域[WOS]Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy
关键词[WOS]CAPILLARY-ELECTROPHORESIS ; PSEUDOURIDINE ; CARCINOMA ; PROTEIN ; MARKERS
英文摘要Modified nucleosides, formed post-transcriptionally in RNA by a number of modification enzymes, are excreted in abnormal levels in the urine of patients with malignant tumors. To test their usefulness as tumor markers, and to compare them with the conventional tumor markers, a reversed-phase high-performance liquid chromatographic (RP-HPLC) method and a factor analysis method have been used to study the excretion pattern of nucleosides of breast cancer patients. A clear cut differentiation of the breast cancer group and the healthy individuals in two clusters without overlapping was obtained. Copyright (C) 2000 John Wiley & Sons, Ltd.
语种英语
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WOS记录号WOS:000165458200002
引用统计
被引频次:44[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/84029
专题中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
2.Med Univ Klin, D-72076 Tubingen, Germany
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GB/T 7714
Xu, G,Schmid, HR,Lu, X,et al. Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method[J]. BIOMEDICAL CHROMATOGRAPHY,2000,14(7):459-463.
APA Xu, G,Schmid, HR,Lu, X,Liebich, HM,&Lu, P.(2000).Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method.BIOMEDICAL CHROMATOGRAPHY,14(7),459-463.
MLA Xu, G,et al."Excretion pattern investigation of urinary normal and modified nucleosides of breast cancer patients by RP-HPLC and factor analysis method".BIOMEDICAL CHROMATOGRAPHY 14.7(2000):459-463.
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