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题名: Mini-electrochemical detector for microchip electrophoresis
作者: Jiang, L;  Lu, Y;  Dai, ZP;  Xie, MH;  Lin, BC
通讯作者: 林炳承
刊名: LAB ON A CHIP
发表日期: 2005
DOI: 10.1039/b505467b
卷: 5, 期:9, 页:930-934
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1807
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Multidisciplinary ;  Nanoscience & Nanotechnology
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry ;  Science & Technology - Other Topics
英文摘要: This paper presents the development of a mini-electrochemical detector for microchip electrophoresis. The small size (3.6 x 5.0 cm(2), W x L) of the detector is compatible with the dimension of the microchip. The use of universal serial bus (USB) ports facilitates installation and use of the detector, miniaturizes the detector, and makes it ideal for lab-on-a-chip applications. A fixed 10 M Omega feedback resistance was chosen to convert current of the working electrode to voltage with second gain of 1, 2, 4, 8, 16, 32, 64 and 128 for small signal detection instead of adopting selectable feedback resistance. Special attention has been paid to the power support circuitry and printed circuit board (PCB) design in order to obtain good performance in such a miniature size. The working electrode potential could be varied over a range of +/-2.5 V with a resolution of 0.01 mV. The detection current ranges from -0.3 x 10(-7) A to 2.5 x 10(-7) A and the noise is lower than 1 pA. The analytical performance of the new system was demonstrated by the detection of epinephrine using an integrated PDMS/glass microchip with detection limit of 2.1 mu M (S/N = 3).
关键词[WOS]: CAPILLARY-ELECTROPHORESIS ;  ELECTROLESS DEPOSITION ;  AMPEROMETRIC DETECTION ;  SYSTEMS ;  DEVICE ;  DECOUPLER
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000231247200002
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/92417
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Dalian 116023, Peoples R China
3.Beijing Sport Univ, Dept Human Sport Sci, Beijing 100084, Peoples R China

Recommended Citation:
Jiang, L,Lu, Y,Dai, ZP,et al. Mini-electrochemical detector for microchip electrophoresis[J]. LAB ON A CHIP,2005,5(9):930-934.
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