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题名: Microfluidic devices for the analysis of apoptosis
作者: Qin, JH;  Ye, NN;  Liu, X;  Lin, BC
通讯作者: 林炳承
关键词: apoptosis ;  microfluidics ;  miniaturization ;  systems biology
刊名: ELECTROPHORESIS
发表日期: 2005-10-01
DOI: 10.1002/elps.200500113
卷: 26, 期:19, 页:3780-3788
收录类别: SCI
文章类型: Review
部门归属: 18
项目归属: 1807
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: Apoptosis is the outcome of a metabolic cascade that results in cell death in a controlled manner. Due to its important role in maintaining balance in organisms, in mechanisms of diseases, and tissue homeostasis, apoptosis is of great interest in the emerging fields of systems biology. Research into cell death regulation and efforts to model apoptosis processes have become powerful drivers for new technologies to acquire ever more comprehensive information from cells and cell populations. The microfluidic technology promises to integrate and miniaturize many bioanalytical processes, which offers an alternative platform for the analysis of apoptosis. This review aims to highlight the recent developments of microfluidic devices in measuring the hallmarks as well as the dynamic process of cellular apoptosis. The potential capability and an outlook of microfluidic devices for the study of apoptosis are addressed.
关键词[WOS]: TOTAL ANALYSIS SYSTEMS ;  SINGLE-CELL ANALYSIS ;  CHIP-BASED SYSTEM ;  CYTOMETRIC ANALYSIS ;  CYTOCHROME-C ;  ANNEXIN-V ;  ASSAY ;  PHOSPHATIDYLSERINE ;  ELECTROPHORESIS ;  DISEASE
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000232579700022
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/92689
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dept Biotechnol, Dalian 116023, Peoples R China

Recommended Citation:
Qin, JH,Ye, NN,Liu, X,et al. Microfluidic devices for the analysis of apoptosis[J]. ELECTROPHORESIS,2005,26(19):3780-3788.
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