中国科学院大连化学物理研究所机构知识库
Advanced  
DICP OpenIR  > 中国科学院大连化学物理研究所  > 期刊论文
题名: Preparation of monolithic silica column with strong cation-exchange stationary phase for capillary electrochromatography
作者: Xie, CH;  Hu, JW;  Xiao, H;  Su, XY;  Dong, J;  Tian, RJ;  He, ZK;  Zou, HF
通讯作者: 邹汉法
关键词: electrochromatography ;  silica monolith ;  strong cation-exchange ;  basic pharmaceuticals
刊名: JOURNAL OF SEPARATION SCIENCE
发表日期: 2005-05-01
DOI: 10.1002/jssc.200400101
卷: 28, 期:8, 页:751-756
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1809
产权排名: 1;1
WOS标题词: Science & Technology ;  Physical Sciences
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
英文摘要: A monolithic silica based strong cation-exchange stationary phase was successfully prepared for capillary electrochromatography. The monolithic silica matrix from a sol-gel process was chemically modified by treatment with 3-mercaptopropyltrimethoxysilane followed by a chemical oxidation procedure to produce the desired function. The strong cation-exchange stationary phase was characterized by its substantial and stable electroosmotic flow (EOF), and it was observed that the EOF value of the prepared column remained almost unchanged at different buffer pH values and slowly decreased with increasing phosphate concentration in the mobile phase. The monolithic silica column with strong cation-exchange stationary phase has been successfully employed in the electrochromatographic separation of beta-blockers and alkaloids extracted from traditional Chinese medicines (TCMs). The column efficiencies for the tested beta-blockers varied from 210,000 to 340,000 plates/m. A peak compression effect was observed for atenolol with the mobile phase having a low phosphate concentration.
关键词[WOS]: UREA-HYDROGEN-PEROXIDE ;  DANSYL AMINO-ACIDS ;  CHROMATOGRAPHIC CHARACTERIZATION ;  TRIFLUOROACETIC-ANHYDRIDE ;  PHARMACEUTICAL ANALYSIS ;  LIQUID-CHROMATOGRAPHY ;  REVERSED-PHASE ;  SEPARATION ;  PERFORMANCE ;  OXIDATION
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000229404700007
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/92739
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
2005K087MM6HLX.pdf(415KB)----开放获取--View Download

作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromoto R&A Ctr, Dalian 116011, Peoples R China
2.Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

Recommended Citation:
Xie, CH,Hu, JW,Xiao, H,et al. Preparation of monolithic silica column with strong cation-exchange stationary phase for capillary electrochromatography[J]. JOURNAL OF SEPARATION SCIENCE,2005,28(8):751-756.
Service
 Recommend this item
 Sava as my favorate item
 Show this item's statistics
 Export Endnote File
Google Scholar
 Similar articles in Google Scholar
 [Xie, CH]'s Articles
 [Hu, JW]'s Articles
 [Xiao, H]'s Articles
CSDL cross search
 Similar articles in CSDL Cross Search
 [Xie, CH]‘s Articles
 [Hu, JW]‘s Articles
 [Xiao, H]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
  Add to CiteULike  Add to Connotea  Add to Del.icio.us  Add to Digg  Add to Reddit 
文件名: 2005K087MM6HLX.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Powered by CSpace