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Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts
Li, QR; Tan, L; Wang, C; Li, N; Li, YS; Xu, GW; Li, JS; Li JS(黎介寿); Li JS(黎介寿)
KeywordPolyunsaturated Fatty Acids Eicosapentaenoic Acid Lipid Rafts Lipid Composition
Source PublicationEUROPEAN JOURNAL OF NUTRITION
2006-04-01
DOI10.1007/s00394-005-0574-7
Volume45Issue:3Pages:144-151
Indexed BySCI
SubtypeArticle
Department18
Funding Project1808
Contribution Rank2;3
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS SubjectNutrition & Dietetics
WOS Research AreaNutrition & Dietetics
WOS KeywordFATTY-ACIDS ; MEMBRANE ; INHIBITION ; ACTIVATION ; DOMAINS ; DISEASE ; CELLS
AbstractBackground Polyunsaturated fatty acids (PUFAs) modulate immune responses particularly by affecting T cell function and are applied clinically as adjuvant immunosuppressants in the treatment of various inflammatory diseases. However, the molecular mechanisms of PUFA-induced immunosuppressive effects are not yet elucidated. Membrane lipid rafts are functional plasma membrane microdomains characterized by a unique lipid environment. Since lipid interactions are crucial for the formation of lipid rafts, the immunomodulatory effects of PUFAs may be due to changes of fatty acid composition in lipid rafts.
Language英语
URL查看原文
WOS IDWOS:000236201500003
Citation statistics
Cited Times:36[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/92881
Collection中国科学院大连化学物理研究所
Corresponding AuthorLi JS(黎介寿); Li JS(黎介寿)
Affiliation1.Jinling Hosp, Inst Gen Surg, Nanjing 210002, Peoples R China
2.Chinese Acad Sci, Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian, Peoples R China
Recommended Citation
GB/T 7714
Li, QR,Tan, L,Wang, C,et al. Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts[J]. EUROPEAN JOURNAL OF NUTRITION,2006,45(3):144-151.
APA Li, QR.,Tan, L.,Wang, C.,Li, N.,Li, YS.,...&黎介寿.(2006).Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts.EUROPEAN JOURNAL OF NUTRITION,45(3),144-151.
MLA Li, QR,et al."Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts".EUROPEAN JOURNAL OF NUTRITION 45.3(2006):144-151.
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