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Identification of phospholipid structures in human blood by direct-injection quadrupole-linear ion-trap mass spectrometry
Wang, C; Yang, J; Gao, P; Lu, X; Xu, GW; Xu GW(许国旺); Xu GW(许国旺)
刊名RAPID COMMUNICATIONS IN MASS SPECTROMETRY
2005
DOI10.1002/rcm.2080
19期:17页:2443-2453
收录类别SCI
文章类型Article
部门归属18
项目归属1808
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences ; Technology
类目[WOS]Chemistry, Analytical ; Spectroscopy
研究领域[WOS]Chemistry ; Spectroscopy
关键词[WOS]PERFORMANCE LIQUID-CHROMATOGRAPHY ; FAST-ATOM-BOMBARDMENT ; ELECTROSPRAY-IONIZATION ; BACTERIAL PHOSPHOLIPIDS ; COOKED BEEF ; PHOSPHATIDYLCHOLINE ; SEPARATION ; LIPIDS ; GLYCEROPHOSPHOLIPIDS ; SPHINGOMYELIN
英文摘要Direct-injection electrospray ionization mass spectrometry in combination with information-dependent data acquisition (IDA), using a triple-quadrupole/linear ion trap combination, allows high-throughput qualitative analysis of complex phospholipid species from child whole blood. In the IDA experiments, scans to detect specific head groups (precursor ion or neutral loss scans) were used as survey scans to detect phospholipid classes. An enhanced resolution scan was then used to confirm the mass assignments, and the enhanced product ion scan was implemented as a dependent scan to determine the composition of each phospholipid class. These survey and dependent scans were performed sequentially and repeated for the entire duration of analysis, thus providing the maximum information from a single injection. In this way, 50 different phospholipids belonging to the phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, phosphatidylcholine and sphingomyelin classes were identified in child whole blood. Copyright (C) 2005 John Wiley & Sons, Ltd.
语种英语
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WOS记录号WOS:000231654100010
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/92885
专题中国科学院大连化学物理研究所
通讯作者Xu GW(许国旺); Xu GW(许国旺)
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
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GB/T 7714
Wang, C,Yang, J,Gao, P,et al. Identification of phospholipid structures in human blood by direct-injection quadrupole-linear ion-trap mass spectrometry[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2005,19(17):2443-2453.
APA Wang, C.,Yang, J.,Gao, P.,Lu, X.,Xu, GW.,...&许国旺.(2005).Identification of phospholipid structures in human blood by direct-injection quadrupole-linear ion-trap mass spectrometry.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,19(17),2443-2453.
MLA Wang, C,et al."Identification of phospholipid structures in human blood by direct-injection quadrupole-linear ion-trap mass spectrometry".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 19.17(2005):2443-2453.
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