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题名: Application of capillary zone electrophoresis in the separation and determination of the curcuminoids in urine
作者: Yuan, KL;  Weng, QF;  Zhang, HY;  Xiong, JH;  Xu, GW
通讯作者: 许国旺
关键词: curcuminoids ;  capillary zone electrophoresis ;  urine ;  Curcuma longa
刊名: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
发表日期: 2005-06-01
DOI: 10.1016/j.jpba.2004.12.009
卷: 38, 期:1, 页:133-138
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1808
产权排名: 1;1
WOS标题词: Science & Technology ;  Physical Sciences ;  Life Sciences & Biomedicine
类目[WOS]: Chemistry, Analytical ;  Pharmacology & Pharmacy
研究领域[WOS]: Chemistry ;  Pharmacology & Pharmacy
英文摘要: The major components of the plant curcuma longa are the curcuminoids that include curcumin, demethoxycurcumin and bisdemethoxycurcumin. It has been reported the curcuminoids have some important activities. A new CZE method with diode array detection has been developed for the separation and determination of the curcumin, demethoxycurcumin and bisdemethoxycurcumin. Three curcuminoids could be readily separated within 7 min with a 15 mM sodium tetraborate buffer containing 10% methanol (v/v) at pH 10.8, 25 kV and 30 degrees C. The method has been validated and shows good performance with respect to selectivity, reproducibility, linearity, limits of detection and recovery. The proposed method was successfully applied to determine the curcuminoids in urine. (c) 2004 Elsevier B.V. All rights reserved.
关键词[WOS]: PERFORMANCE LIQUID-CHROMATOGRAPHY ;  CURCUMA-LONGA ;  ANTIOXIDANT ;  CELLS
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000230017500021
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/92891
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatograph R&A Ctr, Dalian 116011, Peoples R China

Recommended Citation:
Yuan, KL,Weng, QF,Zhang, HY,et al. Application of capillary zone electrophoresis in the separation and determination of the curcuminoids in urine[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2005,38(1):133-138.
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