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题名: Insight into permeability of protein through microcapsule membranes
作者: Qi, WT;  Ma, J;  Liu, YW;  Liu, XD;  Xiong, Y;  Xie, YB;  Ma, XJ
通讯作者: 马小军
关键词: microcapsules ;  permeability ;  diffusion ;  release ;  mathematical model
刊名: JOURNAL OF MEMBRANE SCIENCE
发表日期: 2006-02-01
DOI: 10.1016/j.memsci.2005.06.027
卷: 269, 期:1-2, 页:126-132
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1802
产权排名: 1;1
WOS标题词: Science & Technology ;  Technology ;  Physical Sciences
类目[WOS]: Engineering, Chemical ;  Polymer Science
研究领域[WOS]: Engineering ;  Polymer Science
英文摘要: The objective of this paper is to analyze the characteristics of protein permeability in alainate-polylysine-alginate (APA) and alginate-chitosan-alginate (ACA) microcapsules by mathematical models based on the balance of chemical potential. The comparison between calculated results and experimental data shows that the models can describe the process of protein diffusion from microcapsule and protein release into microcapsule successfully. The influences of membrane composition on the permeability of ACA microcapsule have been investigated and analyzed. The effect of resistance on the mass transfer is further analyzed theoretically with the aid of mathematical modeling. (c) 2005 Elsevier B.V. All rights reserved.
关键词[WOS]: ALGINATE BEADS ;  DIFFUSION ;  DELIVERY ;  CELLS
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000234755800013
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/93539
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dept Sci & Technol, Dalian 116023, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

Recommended Citation:
Qi, WT,Ma, J,Liu, YW,et al. Insight into permeability of protein through microcapsule membranes[J]. JOURNAL OF MEMBRANE SCIENCE,2006,269(1-2):126-132.
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