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题名: A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges
作者: Han, QB;  Yang, L;  Wang, YL;  Qiao, CF;  Song, JZ;  Sun, HD;  Xu, HX
通讯作者: Hong-Xi Xu
刊名: CHEMISTRY & BIODIVERSITY
发表日期: 2006
卷: 3, 期:1, 页:101-105
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1806
产权排名: 2;2
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemistry & Molecular Biology ;  Chemistry, Multidisciplinary
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: Two new polyprenylated xanthone epimers were isolated from gamboges of Garcillia hanburyi, and identified by detailed spectroscopic analysis as 30-hydroxygambogic acid (2a) and its (2S)-epimer 30-hydroxyepigambogic acid (2b). Both compounds exhibited significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines (Table 2).
关键词[WOS]: GARCINIA-HANBURYI ;  IN-VITRO ;  ACID ;  CELLS ;  PROLIFERATION ;  APOPTOSIS ;  ASSAY
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000234987000013
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/93687
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Inst Chinese Med, Hong Kong Jockey Club, Lab Chinese Med, Hong Kong, Hong Kong, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resources Discovery, Dalian 116023, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

Recommended Citation:
Han, QB,Yang, L,Wang, YL,et al. A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges[J]. CHEMISTRY & BIODIVERSITY,2006,3(1):101-105.
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