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Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes
Luo, Yong; Wu, Dapeng; Zeng, Shaojiang; Gai, Hongwei; Long, Zhicheng; Shen, Zheng; Dai, Zhongpeng; Qin, Jianhua; Lin, Bingcheng; Qin JH(秦建华); Lin BC(林炳承); Qin JH(秦建华); Lin BC(林炳承)
Source PublicationANALYTICAL CHEMISTRY
2006-09-01
DOI10.1021/ac0605142
Volume78Issue:17Pages:6074-6080
Indexed BySCI
SubtypeArticle
Department18
Funding Project1807
Contribution Rank1;1
WOS HeadingsScience & Technology ; Physical Sciences
WOS SubjectChemistry, Analytical
WOS Research AreaChemistry
WOS KeywordCAPILLARY ELECTROPHORESIS ; MICROCHIP ELECTROPHORESIS ; MICROFLUIDIC CHIPS ; HYDRODYNAMIC INJECTION ; FLOW ; PERFORMANCE ; SYSTEM ; DEVICES ; SEPARATIONS
AbstractA novel sample injection method for chip CE was presented. This injection method uses hydrostatic pressure, generated by emptying the sample waste reservoir, for sample loading and electrokinetic force for dispensing. The injection was performed on a double-cross microchip. One cross, created by the sample and separation channels, is used for formation of a sample plug. Another cross, formed by the sample and controlling channels, is used for plug control. By varying the electric field in the controlling channel, the sample plug volume can be linearly adjusted. Hydrostatic pressure takes advantage of its ease of generation on a microfluidic chip, without any electrode or external pressure pump, thus allowing a sample injection with a minimum number of electrodes. The potential of this injection method was demonstrated by a four-separation-channel chip CE system. In this system, parallel sample separation can be achieved with only two electrodes, which is otherwise impossible with conventional injection methods. Hydrostatic pressure maintains the sample composition during the sample loading, allowing the injection to be free of injection bias.
Language英语
URL查看原文
WOS IDWOS:000240158000024
Citation statistics
Cited Times:27[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://cas-ir.dicp.ac.cn/handle/321008/97221
Collection中国科学院大连化学物理研究所
Corresponding AuthorQin JH(秦建华); Lin BC(林炳承); Qin JH(秦建华); Lin BC(林炳承)
AffiliationChinese Acad Sci, Dalian Inst Chem Phys, Lab Microfluid Syst Biol, Dalian, Liaoning Prov, Peoples R China
Recommended Citation
GB/T 7714
Luo, Yong,Wu, Dapeng,Zeng, Shaojiang,et al. Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes[J]. ANALYTICAL CHEMISTRY,2006,78(17):6074-6080.
APA Luo, Yong.,Wu, Dapeng.,Zeng, Shaojiang.,Gai, Hongwei.,Long, Zhicheng.,...&林炳承.(2006).Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes.ANALYTICAL CHEMISTRY,78(17),6074-6080.
MLA Luo, Yong,et al."Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes".ANALYTICAL CHEMISTRY 78.17(2006):6074-6080.
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