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Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes
Luo, Yong; Wu, Dapeng; Zeng, Shaojiang; Gai, Hongwei; Long, Zhicheng; Shen, Zheng; Dai, Zhongpeng; Qin, Jianhua; Lin, Bingcheng; Qin JH(秦建华); Lin BC(林炳承); Qin JH(秦建华); Lin BC(林炳承)
刊名ANALYTICAL CHEMISTRY
2006-09-01
DOI10.1021/ac0605142
78期:17页:6074-6080
收录类别SCI
文章类型Article
部门归属18
项目归属1807
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]CAPILLARY ELECTROPHORESIS ; MICROCHIP ELECTROPHORESIS ; MICROFLUIDIC CHIPS ; HYDRODYNAMIC INJECTION ; FLOW ; PERFORMANCE ; SYSTEM ; DEVICES ; SEPARATIONS
英文摘要A novel sample injection method for chip CE was presented. This injection method uses hydrostatic pressure, generated by emptying the sample waste reservoir, for sample loading and electrokinetic force for dispensing. The injection was performed on a double-cross microchip. One cross, created by the sample and separation channels, is used for formation of a sample plug. Another cross, formed by the sample and controlling channels, is used for plug control. By varying the electric field in the controlling channel, the sample plug volume can be linearly adjusted. Hydrostatic pressure takes advantage of its ease of generation on a microfluidic chip, without any electrode or external pressure pump, thus allowing a sample injection with a minimum number of electrodes. The potential of this injection method was demonstrated by a four-separation-channel chip CE system. In this system, parallel sample separation can be achieved with only two electrodes, which is otherwise impossible with conventional injection methods. Hydrostatic pressure maintains the sample composition during the sample loading, allowing the injection to be free of injection bias.
语种英语
原文出处查看原文
WOS记录号WOS:000240158000024
引用统计
被引频次:27[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/97221
专题中国科学院大连化学物理研究所
通讯作者Qin JH(秦建华); Lin BC(林炳承); Qin JH(秦建华); Lin BC(林炳承)
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Lab Microfluid Syst Biol, Dalian, Liaoning Prov, Peoples R China
推荐引用方式
GB/T 7714
Luo, Yong,Wu, Dapeng,Zeng, Shaojiang,et al. Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes[J]. ANALYTICAL CHEMISTRY,2006,78(17):6074-6080.
APA Luo, Yong.,Wu, Dapeng.,Zeng, Shaojiang.,Gai, Hongwei.,Long, Zhicheng.,...&林炳承.(2006).Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes.ANALYTICAL CHEMISTRY,78(17),6074-6080.
MLA Luo, Yong,et al."Double-cross hydrostatic pressure sample injection for chip CE: Variable sample plug volume and minimum number of electrodes".ANALYTICAL CHEMISTRY 78.17(2006):6074-6080.
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