DICP OpenIR
Analysis of estrogenic compounds in Polygonum cuspidatum by bioassay and high performance liquid chromatography
Zhang, CN; Zhang, XZ; Zhang, Y; Xu, Q; Xiao, HB; Liang, XM; Liang XM(梁鑫淼); Liang XM(梁鑫淼)
关键词Polygonum Cuspidatum Anthraquinone Estrogenic Activity Emodin
刊名JOURNAL OF ETHNOPHARMACOLOGY
2006-04-21
DOI10.1016/j.jep.2005.10.029
105期:1-2页:223-228
收录类别SCI
文章类型Article
部门归属18
项目归属1804,1803
产权排名1;1
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
关键词[WOS]DIETARY PHYTOESTROGENS ; MENOPAUSAL SYMPTOMS ; IN-VITRO ; REPLACEMENT ; EXTRACTS ; THERAPY ; CANCER ; WOMEN
英文摘要The estrogenic activity of traditional Chinese herb-Polygonum cuspidation Sieb. et Zucc. was investigated by a recombinant yeast screening (YES) assay. Anthraquinones are the main components in the plant, of which emodin is the most abundant one. The ethyl acetate fraction of the ethanol extract of Polygonum cuspidatum was separated on a silica gel TLC plate and seven sub-fractions were collected. The results of bioassay demonstrated that Hzs1 and Hzs6 showed higher estrogenic activities than that of others and the potency of these two compounds were approximately 10(-4) g/L and 10(-3) g/L, respectively. HPLC analysis was performed to determine the activities and the active components. Combining the results of HPLC analysis and estrogenic activity test by YES led to the conclusion that an unknown bioactive compound might exist in the extraction of Polygonum cuspidatum. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
语种英语
原文出处查看原文
WOS记录号WOS:000237101300031
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/97427
专题中国科学院大连化学物理研究所
通讯作者Liang XM(梁鑫淼); Liang XM(梁鑫淼)
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Zhang, CN,Zhang, XZ,Zhang, Y,et al. Analysis of estrogenic compounds in Polygonum cuspidatum by bioassay and high performance liquid chromatography[J]. JOURNAL OF ETHNOPHARMACOLOGY,2006,105(1-2):223-228.
APA Zhang, CN.,Zhang, XZ.,Zhang, Y.,Xu, Q.,Xiao, HB.,...&梁鑫淼.(2006).Analysis of estrogenic compounds in Polygonum cuspidatum by bioassay and high performance liquid chromatography.JOURNAL OF ETHNOPHARMACOLOGY,105(1-2),223-228.
MLA Zhang, CN,et al."Analysis of estrogenic compounds in Polygonum cuspidatum by bioassay and high performance liquid chromatography".JOURNAL OF ETHNOPHARMACOLOGY 105.1-2(2006):223-228.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, CN]的文章
[Zhang, XZ]的文章
[Zhang, Y]的文章
百度学术
百度学术中相似的文章
[Zhang, CN]的文章
[Zhang, XZ]的文章
[Zhang, Y]的文章
必应学术
必应学术中相似的文章
[Zhang, CN]的文章
[Zhang, XZ]的文章
[Zhang, Y]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。