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Quantitative determination of oxidized carbon nanotube probes in yeast by capillary electrophoresis with laser-induced fluorescence detection
Xiao, Hua; Zou, Hanfa; Pan, Chensong; Jiang, Xiaogang; Le, X. Chris; Yang, Ling; Zou HF(邹汉法); Zou HF(邹汉法)
关键词Capillary Electrophoresis Laser-induced Fluorescence Detection Carbon Nanotube Probes Yeast Apparent Permeability Coefficient
刊名ANALYTICA CHIMICA ACTA
2006-11-24
ISSN0003-2670
DOI10.1016/j.aca.2006.07.074
580期:2页:194-199
收录类别SCI
文章类型Article
部门归属18
项目归属1809
产权排名1;1
WOS标题词Science & Technology ; Physical Sciences
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]DRUG-DELIVERY ; TRANSPORTERS ; CANCER ; CELLS ; SEPARATIONS ; FIELD ; DNA
英文摘要Short oxidized multi-walled carbon nanotubes were functionalized with fluorescein isothiocyanate to form carbon nanotube probes (CNTP). The distribution of CNTP in yeast was quantitatively determined by capillary electrophoresis coupled with laser-induced fluorescence detection. The detection sensitivity for CNTP was greatly improved comparing with UV absorbance and Raman detection. The time- and temperature-dependent influx patterns of CNTP into yeast were obtained. The apparent permeability coefficient for influx of CNTP into yeast was calculated, which suggested that CNTP might permeate into yeast through endocytosis. This study implies that CNTP could be a fine drug transporter and might be wildly used in multidrug resistance research and microorganism detection. (c) 2006 Elsevier B.V. All rights reserved.
语种英语
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WOS记录号WOS:000242304800011
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被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://cas-ir.dicp.ac.cn/handle/321008/97439
专题中国科学院大连化学物理研究所
通讯作者Zou HF(邹汉法); Zou HF(邹汉法)
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatograph R&A Ctr, Dalian 116023, Peoples R China
2.Univ Alberta, Fac Med, Dept Publ Hlth Sci, Edmonton, AB T6G 2G3, Canada
3.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China
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Xiao, Hua,Zou, Hanfa,Pan, Chensong,et al. Quantitative determination of oxidized carbon nanotube probes in yeast by capillary electrophoresis with laser-induced fluorescence detection[J]. ANALYTICA CHIMICA ACTA,2006,580(2):194-199.
APA Xiao, Hua.,Zou, Hanfa.,Pan, Chensong.,Jiang, Xiaogang.,Le, X. Chris.,...&邹汉法.(2006).Quantitative determination of oxidized carbon nanotube probes in yeast by capillary electrophoresis with laser-induced fluorescence detection.ANALYTICA CHIMICA ACTA,580(2),194-199.
MLA Xiao, Hua,et al."Quantitative determination of oxidized carbon nanotube probes in yeast by capillary electrophoresis with laser-induced fluorescence detection".ANALYTICA CHIMICA ACTA 580.2(2006):194-199.
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