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题名: A hybrid microdevice with a thin PDMS membrane on the detection window for UV absorbance detection
作者: Ma, Bo;  Zhou, Xiaomian;  Wang, Gang;  Dai, Zhongpeng;  Qin, Jianhua;  Lin, Bingcheng
通讯作者: 林炳承
关键词: hybrid microchip ;  PDMS ;  quartz ;  UV detection
刊名: ELECTROPHORESIS
发表日期: 2007-07-01
DOI: 10.1002/elps.200600619
卷: 28, 期:14, 页:2474-2477
收录类别: SCI
文章类型: Article
部门归属: 18
项目归属: 1807
产权排名: 1;1
WOS标题词: Science & Technology ;  Life Sciences & Biomedicine ;  Physical Sciences
类目[WOS]: Biochemical Research Methods ;  Chemistry, Analytical
研究领域[WOS]: Biochemistry & Molecular Biology ;  Chemistry
英文摘要: We exploited a PDMS-quartz hybrid microchip with a thin PDMS membrane on the concave detection window for UV absorbance detection. The thickness of the PDMS membrane is about 100 pm, with high UV transmittance. As compared to a PDMS-quartz hybrid chip with a common detection window, the proposed one exhibited over an one order of magnitude sensitivity enhancement, and an about two orders of magnitude S/N increase for gastrodin (p-hydroxymethylphenyl-beta-D-glucopyranoside). In addition, the limit of the detection wavelength has been extended from 240 to 210 nm, which is otherwise impossible for a traditional PDMS-quartz hybrid microchip. This kind of microchip has the potential for a large range of applications in an integrated microfluidic system with UV detection.
关键词[WOS]: MICROFLUIDIC DEVICES ;  CAPILLARY-ELECTROPHORESIS ;  SEPARATION ;  POLY(DIMETHYLSILOXANE) ;  SYSTEMS ;  QUARTZ ;  FABRICATION ;  MICROCHIP ;  CHIPS ;  POLYMERS
语种: 英语
原文出处: 查看原文
WOS记录号: WOS:000248390900019
Citation statistics: 
内容类型: 期刊论文
URI标识: http://cas-ir.dicp.ac.cn/handle/321008/98697
Appears in Collections:中国科学院大连化学物理研究所_期刊论文

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作者单位: 1.Chinese Acad Sci, Dalian Inst Chem Phys, Grad Sch, Dalian 116023, Peoples R China
2.Guangzhou Med Coll, Guangzhou Municipal Peoples Hosp 1, Dept Clin Lab, Guangzhou, Peoples R China

Recommended Citation:
Ma, Bo,Zhou, Xiaomian,Wang, Gang,et al. A hybrid microdevice with a thin PDMS membrane on the detection window for UV absorbance detection[J]. ELECTROPHORESIS,2007,28(14):2474-2477.
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